0:00
Hello, my name is
Catherine Gadelha.
I'm a reader in
Molecular Cell Biology
at the University of Nottingham.
My research topic is
host-parasite interactions,
with a particular focus on
the cell surface receptors
and ligands that enable
these interactions.
In this lecture on
parasite immunity,
which is divided into two parts,
I plan to cover four areas.
First, I will give a
brief overview of scales
across parasites and
why size matters.
Then I will discuss
the immunity to
three major parasitic
diseases of humans.
Malaria, leishmaniasis
and schistosomiasis.
0:48
Taking you on a quick journey
through size and scale,
which are really important
in biological systems.
0:57
I will start at the metre scale
and the parasite I will use
to exemplify this scale
is the cestode Taenia
solium, or pork tapeworm,
which can grow up to
three metres long.
Moving down the scale
an order of magnitude
and fitting the next slide to
this square here at the
bottom right corner.
1:23
I'm moving from the metre
scale to ten centimetres.
We have, for example,
the nematode
Ascaris lumbricoides
or round worm.
This can grow up
to 25 centimetres,
10 times smaller than
the previous cestode,
but still very large.
