Inorganic nanostructured interfaces for therapeutic delivery

Published on July 31, 2018   27 min

Other Talks in the Series: Drug Delivery

Other Talks in the Series: Periodic Reports: Advances in Clinical Interventions and Research Platforms

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Hello, my name is Tejal Desai, and I'm a professor and chair of the Department of Bioengineering and Therapeutic Sciences at UCSF. Today, I am talking about "Inorganic Nanostructured Interfaces for Therapeutic Delivery". An area that we've worked in for many years, related to how we can create nanostructured materials to influence how we deliver drugs to the body.
For our educational objectives today, I hope we can gain a basic understanding of nanotechnology and its implications for biology and particular therapeutic delivery, and to gain exposure of some of the current challenges facing drug delivery. Finally, I hope that you will understand ways in which inorganic nanostructured materials can be used to enhance therapeutic delivery.
To get started, I just want to introduce everyone to the scale of materials, and how we think about nanostructures versus micro and macro structures. The nanotechnology world really lives in a very small domain. Things that are less than 100 nanometers or so. So smaller than red blood cells, smaller than a human hair, and really on the scale of proteins and biologic molecules. This is where we're interested in really creating materials that can interface with the body.
And while there are many many nanomaterials that had been developed, in particular what I'll talk to you today about, are materials in which we take existing micro or macro materials, and actually nanostructure the interface. So, this image that is on your right, which shows a nanotextured or nanoporous implant, that can be used in many different ways. Why are we interested in this?

Inorganic nanostructured interfaces for therapeutic delivery

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