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Hello. My name is
Dr. Pravin Shende,
I am Professor and PG
Chairperson at SVKM's and NMIMS,
Shobhaben Pratapbhai
Patel School of
Pharmacy and
Technology Management,
Mumbai, India.
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This is my research contributions
and accomplishments.
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It's my pleasure to
introduce the topic
regarding different transporters
in drug delivery systems.
I am going to tell you
about multiple approaches
for delivery via transporters
present in the human body.
Outline on the substrates
and inhibitors of
transporters that
affect delivery
and their pharmacological
applications.
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Most transporters show a
site-specific expression
which provides ideal targets
for drug delivery to
increase uptake at
specific site or enhanced
permeation across
biological barriers
such as blood-brain barrier.
In bio-transporters,
movement of drugs from
one biological barrier to
another side of the cell is
guided via transport mechanism.
Membrane-associated
proteins that govern
the transport of solutes,
for example, drugs and
other xenobiotics into
and out of the cells.
Transporters can play a
vital role in determining
the drug concentrations in
systemic circulation
and in cells.
The two major super families of
membrane transporters are
ATP Binding Cassette,
ABC and Solute Carrier
SLC Super Families.
