Hello. My name's Dr. Annaliesa Anderson and I'm
the Chief Scientific Officer for bacterial vaccines at Pfizer.
My disclosure is that I work for Pfizer and as such,
I'm paid by Pfizer.
Today I'm going to talk about the importance of vaccines in reducing
antibiotic exposure and preventing antimicrobial resistance.
I'll be conducting this lecture in two parts.
The first part, we'll introduce what
antimicrobial resistance is and discuss its emergence and spread.
I'll explain how vaccines differ from
antibiotics in their mechanism of action and I'll also give
some examples of licensed vaccines that have had
a documented and proven ability to fight antimicrobial resistance.
In my second part of this lecture,
I will be giving some examples where vaccines
don't currently assist against specific pathogens that of
concern for antimicrobial resistance and the work that is being
done to develop vaccines that can protect against these diseases.
I'll be giving an overview of the global mobilization actions by
different agencies to implement the use of vaccines to prevent antimicrobial resistance.
I'll discuss barriers to maximizing licensed vaccines in the fight against
AMR and talk about efforts that are being
made towards better utilization of vaccines against AMR.
In this first section,
I'll talk about the emergence and spread of antimicrobial resistance.
Antimicrobial resistance is a natural evolutionary process.
It occurs when pathogens such as bacteria change and
find ways to resist the effect of the drugs that are used to treat them,
in this case, antibiotics.
The pathogens can survive, grow,
and spread their resistance to other bacteria and
this process of adaptation leads to antimicrobial resistance.