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Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- Infectious diseases
- Immunization (vaccination)
- Immunization
- Process of defense mechanisms
- With and without antibody scenarios
- Vaccine formulation
- Thiomersal (thimerosal) safety
- Antigen
- Antigens (1)
- Antigens (2)
- Examples of antigens
- Vaccine delivery routes
- Vaccine delivery systems
- Needle-free injector
- Intranasal spray
- Dissolvable microneedle patches
- History of adjuvants
- Adjuvants (1)
- Adjuvants (2)
- Characteristic properties of adjuvants
- Adjuvants can be classified according to:
- Classifications of adjuvants (1)
- Classifications of adjuvants (2)
- Why micro and nano delivery systems?
- Uptake of particulate systems is influenced by:
- Adjuvants – how they affect the immune system
- Adjuvants and approval
- Adjuvant: “the immunologists' dirty little secret”
- Nobel Prize in Physiology or Medicine (2011)
- Activation of innate immunity
- PRRs (Pattern Recognition Receptors)
- Mechanism of action of adjuvants - scheme
- Adjuvants approved with the product (1)
- Adjuvants approved with the product (2)
- Adjuvants approved with the product (3)
- Storage of vaccines
- Cold-chain
- Edible plant-derived vaccines
- Therapeutic vaccines
- Successful vaccine formulation
- Thank you
Topics Covered
- Introduction to immunization (prophylactic vaccines)
- Vaccine formulation
- Types of antigens
- Vaccine delivery routes (parenteral, mucosal, cutaneous)
- Vaccine delivery systems (needle and syringe, needle-free systems)
- Vaccine adjuvants (history, classification, mechanism of action)
- Adjuvants approved with the product
- Edible plant-based vaccines and therapeutic vaccines
Talk Citation
Şenel, S. (2019, April 30). Vaccine delivery [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 7, 2024, from https://doi.org/10.69645/YTWE6321.Export Citation (RIS)
Publication History
Financial Disclosures
- Professor Sevda Şenel has no commercial/financial relationships to disclose
Other Talks in the Series: Drug Delivery
Transcript
Please wait while the transcript is being prepared...
0:00
Hello. I'm Professor Sevda Senel from
Hacettepe University Department of
Pharmaceutical Technology, which is based in Ankara, Turkey.
Today, I will give you a brief introduction on
vaccine delivery science, which is my main research area.
0:22
In my presentation, I will first give a brief introduction to immunization;
then, I will talk about vaccine formulation ingredients and types of antigens,
and, also, how we deliver these vaccines,
which routes we use,
and which delivery systems we use for vaccine preparations.
The adjuvants, which are most important for vaccine delivery
I will go into much deeper detail,
and I will give some examples of the approved adjuvants,
and, also, mention about their mechanisms.
Finally, I will very briefly mention about
the different approaches to obtain
vaccine antigens, which are edible plant-based vaccines.
In my presentation, I will talk only on prophylactic vaccines
but, we know that there are therapeutic vaccines.
I will give a very brief introduction and
information about the therapeutic vaccines as well,
and finally, I will conclude on how to have a successful vaccine formulation.