Hi, I'm Judy Gault.
I'm a Research Associate Professor,
engaged in schizophrenia research at
the University of Colorado in the Departments of Neurosurgery and Psychiatry.
Today's presentation is on
deep brain stimulation and its use for neuromodulation in schizophrenia,
specifically, treatment refractory schizophrenia.
So, the overview for my presentation for
deep brain stimulation for schizophrenia is to first,
go over the general characteristics of schizophrenia.
Then, discuss the unmet needs in patients with schizophrenia,
and in the treatment refractory population.
Then, discuss whether this patient population
is actually amenable to deep brain stimulation.
Then, we'll ask the question of whether schizophrenia,
is a circuit disorder like Parkinson's disease,
and a central tremor, and dystonia.
These are disorders that are currently being treated with deep brain stimulation,
and we'll ask the question,
is schizophrenia circuit disorder like these
and therefore amenable to deep brain stimulation?
If so, what are the targets?
What are the risks?
We need to discuss the ethics and when do the benefits outweigh the risks.
The image is of a patient who actually has a deep brain stimulation unit implanted
and you can see what it entails in terms of the leads
and the connection to a neuromodulation pulse generator.