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0:00
Hello, I'm Renad AlAnsari from
the School of Medicine at
the Royal College of
Surgeons in Ireland,
Medical University of Bahrain.
My colleague, Bushra and
I are attached to
the Materials for
Medicine Research Group
led by Dr. Roshan Deen.
The main research focus of
our group is the development
of new materials like stimuli
responsive hydrogels,
nanocomposites, and
green nanoparticles for
biomedical applications.
In this lecture, we will
be talking about the use
of liposomes as drug
delivery systems.
I'll be presenting the first
section of this lecture,
and Bushra will be presenting
the second section.
0:38
By the end of this lecture,
you should be able
define liposomes
and list their advantages.
Recall examples of liposomal
drug delivery systems
in the market and what
they're used for.
List the different types of
liposomal drug delivery systems
and explain how
each one functions.
Finally, list and
understand the challenges
to using liposomes as
drug delivery systems.
1:03
Now we're going to talk
about the need for
targeted drug delivery systems.
In the treatment of disease
the drug or the therapeutic
agent needs to be
available at the target site
and at the right concentration.
If the pharmacokinetics is poor,
the bioavailability of
the drug is limited and
could lead to toxicity
of tissues at off sites.
Now this is where the importance
of nanotechnology
and nanomedicine
is fully recognized in
the development of targeted
drug delivery systems.
Nanotechnology plays
a very important role in
translational research,
particularly in the
field of medicine.
Using this technology,
the disease can be
diagnosed and treated
at the clinical level.
Nanoparticles and
liposomes are widely
used in the development of
targeted drug delivery and
gene delivery systems
for the delivery of
various drugs and genes to
the target sites
in the human body.