Other Talks in the Series: Drug Delivery

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Hello, I'm Renad AlAnsari from the School of Medicine at the Royal College of Surgeons in Ireland, Medical University of Bahrain. My colleague, Bushra and I are attached to the Materials for Medicine Research Group led by Dr. Roshan Deen. The main research focus of our group is the development of new materials like stimuli responsive hydrogels, nanocomposites, and green nanoparticles for biomedical applications. In this lecture, we will be talking about the use of liposomes as drug delivery systems. I'll be presenting the first section of this lecture, and Bushra will be presenting the second section.
By the end of this lecture, you should be able define liposomes and list their advantages. Recall examples of liposomal drug delivery systems in the market and what they're used for. List the different types of liposomal drug delivery systems and explain how each one functions. Finally, list and understand the challenges to using liposomes as drug delivery systems.
Now we're going to talk about the need for targeted drug delivery systems. In the treatment of disease the drug or the therapeutic agent needs to be available at the target site and at the right concentration. If the pharmacokinetics is poor, the bioavailability of the drug is limited and could lead to toxicity of tissues at off sites. Now this is where the importance of nanotechnology and nanomedicine is fully recognized in the development of targeted drug delivery systems. Nanotechnology plays a very important role in translational research, particularly in the field of medicine. Using this technology, the disease can be diagnosed and treated at the clinical level. Nanoparticles and liposomes are widely used in the development of targeted drug delivery and gene delivery systems for the delivery of various drugs and genes to the target sites in the human body.