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Printable Handouts
Navigable Slide Index
- Introduction
- The microbiome in the news
- Microbiome components
- Population comparisons
- The diversity of microbes
- Evolution of the desert rat
- The gut-brain axis
- The microbiome and obesity
- Variation in skin microbiome
- Shaping the adult microbiome
- Gut barrier function
- Immune development
- Manipulating the microbiome
- The good, the bad, the ugly
- Potential side effects
- Correlation vs. causation
- Different bacterial populations
- Data production
- Bacterial families
- Microbiome diversity
- The future
- The spread of bacteria
- Thank you
Topics Covered
- The composition of the microbiome
- The influence of the microbiome on behaviour and health
- Factors that affect microbiome composition
- Faecal microbial transplants
- Variation of bacterial species within the gut
- The potential for microbiome alteration in the future
Links
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Talk Citation
Cruickshank, S. (2019, April 30). Immunology, the microbiome and future perspectives [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/JHLO2876.Export Citation (RIS)
Publication History
Financial Disclosures
- Professor Sheena Cruickshank has no commercial/financial relationships to disclose
Other Talks in the Series: Periodic Reports: Advances in Clinical Interventions and Research Platforms
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, my name is Professor Sheena Cruikshank,
I'm an Immunologist from
the University of Manchester and I'm going to be talking today about
immunology and the microbiome and some future perspectives in microbiome research.
0:16
The reason I think the microbiome is so interesting
is that the moment more than ever we are just being assaulted
with lots and lots of headlines and
information about the microbiome where it's being linked with
a whole host of things from health and happiness to our well-being, sleep, depression.
Everything is being linked to the microbiome and there's
a huge market and how to manipulate the microbiome with things
like probiotics market being worth billions and recipes to alter your microbiome in
some really extreme suggestions and
health sites as to what you can do to really change your microbiome.
But how much of this is fact,
how much of this is fiction,
and to really start to unpick that I think it's really important that we
start to understand what we mean by the microbiome.
There are two terms that are usually used when we're talking about the microbiome and
that is microbiota which tends to refer to
the species that are present in and on our bodies,
and the microbiome which refers to
the genetic content and that's
the way that I will try and use those terms throughout this talk.
1:25
When I talk about the microbiome,
what I'm referring to is the organisms that live
inside us and on us and these include yeast,
fungi, bacteria, and viruses and even a few parasites.
But at the moment we know the most about the bacteria that live inside us and on us
and it's been estimated that there are 38 trillion bacteria resident in us and on us.
So each of us has this huge community of bacteria.