Recent advances in the field of non-coding RNAs in cancer

Published on February 28, 2018   35 min
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Hello everyone, I am Maitri Y. Shah. I'm a Postdoctoral Fellow in Dr. George Calin's lab, at MD Anderson Cancer Center in Houston Texas. Today, I'll be talking about the "Recent Advances in the Field of Non-coding RNAs in Cancer", particularly those in the last two years that have influenced research and clinical practice.
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Integrated use of advanced genome analysis platforms in recent years by consortiums such as the Human Genome Project and the Encyclopedia of DNA Elements or Encode project have revealed that the transcription and processing of the human genome yield a diverse catalog of non-coding RNAs. The protein-coding genes occupy less than two percent of the human genome. These protein-coding genes account for approximately one-third of all annotated genes, whereas long and small non-coding RNAs genes together account for 40 percent of the genes. Considering the ubiquitous presence and diversity, these non-coding RNAs have attracted a lot of attention in the past decade. An extensive research has been performed to understand their role in normal cellular physiological processes as well as in human diseases.
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Recent advances in the field of non-coding RNAs in cancer

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