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Vaccines as a weapon against antibiotic resistance

Published on May 30, 2021   30 min

Other Talks in the Series: Periodic Reports: Advances in Clinical Interventions and Research Platforms

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0:00
Hello, my name is Pumtiwitt McCarthy, I'm an associate professor in the Department of Chemistry at Morgan State University, and today I'll be talking to you about vaccines and how they can be used as a weapon against antibiotic resistance.
0:17
As an overview of my presentation today, I'll first be talking about antibiotic resistance. I will then focus on the major World Health Organization pathogenic targets, with a focus on one species per priority level. I'll talk about the current vaccines against these species, as well as some development that's taking place. At the end I'll provide some conclusions to the presentation.
0:45
Antibiotic resistance is a global problem, and this is mainly because of the fact that there is an overuse of antibiotics. Bacteria are continually evolving, to incorporate new ways to weaken the effect of antibiotics. The World Health Organization has developed a global action plan to help combat antimicrobial resistance.
1:10
In this slide, I have some chemical structures of a few of the antibiotics that currently many bacteria have resistance to, including penicillin, cephalosporins, carbapenems, as well as fluoroquinolones.
1:30
The five strategic goals of the World Health Organization's global action plan are: first, to improve awareness and understanding of antimicrobial resistance; to strengthen knowledge through surveillance and research; to reduce the incidence of infection; to optimize the use of antimicrobial agents; and also to develop the economic case for sustainable investment, that will take into account the needs of all countries, and increase investment in new medicines, diagnostic tools, vaccines and other inventions. I've highlighted what we'll focus on in this presentation, which is vaccines, and vaccines can be very important to reducing the incidence of infection.

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