Hello, my name is Pumtiwitt McCarthy,
I'm an associate professor in the Department of Chemistry
at Morgan State University, and today I'll be
talking to you about vaccines and how they can be
used as a weapon against antibiotic resistance.
As an overview of my presentation today,
I'll first be talking about antibiotic resistance.
I will then focus on the major World Health Organization pathogenic targets,
with a focus on one species per priority level.
I'll talk about the current vaccines against these species, as well as
some development that's taking place.
At the end I'll provide some conclusions to the presentation.
Antibiotic resistance is a global problem, and this is
mainly because of the fact that there is an overuse of antibiotics.
Bacteria are continually evolving, to incorporate new ways to weaken the effect of antibiotics.
The World Health Organization has developed
a global action plan to help combat antimicrobial resistance.
In this slide, I have some chemical structures of a few of
the antibiotics that currently many bacteria have resistance to,
including penicillin, cephalosporins, carbapenems,
as well as fluoroquinolones.
The five strategic goals of the World Health Organization's global action plan are:
first, to improve awareness and understanding of antimicrobial resistance;
to strengthen knowledge through surveillance and research;
to reduce the incidence of infection;
to optimize the use of antimicrobial agents;
and also to develop the economic case for
sustainable investment, that will take into account the needs
of all countries, and increase investment in new medicines,
diagnostic tools, vaccines and other inventions.
I've highlighted what we'll focus on in this presentation,
which is vaccines, and vaccines can be
very important to reducing the incidence of infection.