Dr. Crowe is Director of the Vanderbilt Vaccine Center and the Ann Scott Carell Professor of Pediatrics, Pathology, Microbiology and Immunology. His laboratory studies the human immune response to infection for a wide variety of major human pathogens, including emerging infections. He is the Director of the Human Immunome Project, an ambitious effort to identify the sequence of all transcripts for human adaptive immune receptors. He is an elected member of the National Academy of Medicine.

Dr. Crowe received his MD degree and pediatrics residency at UNC-Chapel Hill. He received five years of postdoctoral training in the laboratory of Dr. Robert Chanock at the NIH, then completed ID fellowship training in 1996 at Vanderbilt. He has run an independent laboratory at Vanderbilt since then. His research has been supported by a large number of investigator-initiated research awards from NIH, DARPA, DTRA, and foundations. He has trained over 20 investigators who have obtained tenure track positions in academic medical centers.

His work has been published over 350 publications in high-quality journals including Cell, Science, Nature, PNAS USA, the New England Journal of Medicine, and JAMA. He has been the recipient of investigator awards from the March of Dimes, American Society for Microbiology, Pediatric Infectious Diseases Society, and Society for Pediatric Research. He has been awarded the Judson Daland Prize of the American Philosophical Society, the Oswald Avery Award of the IDSA, the Mead Johnson Award for Excellence in Pediatrics, the Outstanding Investigator Award of the American Federation for Medical Research, and the 2010 Siegel Award of the American Pediatric Society. Most recently, he was awarded the 2017 Korsmeyer Award, ASCI and the 2017 the Samuel Rosenthal Foundation Prize in Academic Pediatrics. He is an elected Fellow of AAM, AAAS, ASCI and AAP, IDSA, APS and others. His team was awarded the 2018 Best Academic Research Team, 11th Annual Vaccine Industry Excellence Awards.