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We hope you have enjoyed this free, full length talk
Topics Covered
- Mode of action of the Oxford/AstraZeneca DNA vaccine
- Two potential adverse events reported in patients enrolled in the vaccine’s phase 3 trial
- Steps undertaken to determine possible causality between the adverse events and the vaccine
- Differences between RNA and DNA vaccine properties and mechanism of action
- Current status of the trial
- Please note that since the recording of this interview it was determined that "The serious adverse events observed during the trial in these study groups were judged to be unrelated to the study vaccines and occurred at frequencies expected for these conditions in the general population. None of the participants included in this report had any suspected unexpected serious adverse reactions." (Ramasamy et al., The Lancet, November 18, 2020, https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32466-1/fulltext).
Biography
Prof. Saad Shakir MB ChB LRCP&S FRCP FFPM MRCGP, has been working in pharmacovigilance & pharmacoepidemiology for more than a decade. He is the Director of the Drug Safety Research Unit (DSRU) in Southampton, an academic unit associated with the University of Portsmouth, where he leads a research team with an active program for monitoring and studying the safety of medicines. He has worked and advised on many drug safety issues including product withdrawals and major safety hazards. He is the author of many publications on pharmacovigilance and pharmacoepidemiology and a member of the editorial board of the journals of Pharmacoepidemiology and Drug Safety.
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Talk Citation
Shakir, S. (2020, November 18). Oxford/AstraZeneca COVID-19 vaccine trial: adverse patient event reports [Audio file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 12, 2024, from https://doi.org/10.69645/WRSL8173.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Saad Shakir has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Oxford/AstraZeneca COVID-19 vaccine trial: adverse patient event reports
Other Talks in the Playlist: Interviews on Covid-19
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