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Printable Handouts
Navigable Slide Index
- Introduction
- Overview of presentation
- An ancient disease
- Biology
- Gravid female mite
- Scabies life cycle
- Transmission
- Fomites contribute very little to transmission
- Sacroptes scabiei var. canis
- Pathogenesis and complications
- ‘Classical’ or ‘ordinary’ scabies
- Crusted scabies
- Secondary infection
- Scabies and gram-positive bacteria
- The public health control of scabies
- Epidemiology
- 2016 Global Burden of Disease Study
- The global burden of scabies
- Prevalence of scabies
- Clinical manifestations
- Classic clinical manifestations (1)
- Classic clinical manifestations (2)
- Classic clinical manifestations (3)
- Classic clinical manifestations (4)
- Typical distribution of scabies lesions
- Differential diagnoses of classical scabies
- Diagnosis
- Diagnosis of scabies in therapeutic trials
- Findings
- Clinical features used in therapeutic trials
- Consensus criteria
- Consensus criteria: clinical signs
- Consensus criteria: history
- Consensus criteria: magnifying device
- Direct visualisation of scabies mite
- Consensus criteria: mite and mite products
- Consensus criteria: putting it all together
- Treatment
- Life cycle and treatment
- Treatment of typical scabies
- Cochrane review
- Ivermectin and permethrin for treating scabies
- The trouble with topical treatment
- Index cases vs. household contacts
- WHO model list of essential medicines
- Crusted scabies treatment
- Public health considerations
- Three key features of NTDs
- WHO recommendations
- WHO: framework for scabies control
- Control strategies
- Impact of MDA
- MDA is effective for scabies
- 2015 Nobel Prize for Physiology or Medicine
- Ivermectin in the Solomon Islands
- Reduction in scabies after MDA
- Skin Health Intervention: Fiji Trial (SHIFT)
- SHIFT study results
- SHIFT: prevalence of impetigo
- Are these reductions sustained?
- 2-year follow up: prevalence of scabies
- 2-year follow up: prevalence of impetigo
- AIM study (1)
- AIM study (2)
- AIM study: efficacy (1)
- AIM study: efficacy (2)
- Control programs
- WHO consultation: epidemiology
- WHO consultation: population-level control
- WHO consultation: strategy
- World Scabies Program (WSP)
- WSP overview (1)
- WSP overview (2)
- WSP objectives
- WSP global approach
- WSP country approach (1)
- WSP country approach (2)
- Debunking myths
- Future efforts
Topics Covered
- Scabies
- Biology and transmission of scabies
- Pathogenesis and complications of scabies
- Epidemiology and clinical manifestations of scabies
- Diagnosis and treatment of scabies
- Control strategies and programs for scabies
Links
Series:
Categories:
Therapeutic Areas:
External Links
Talk Citation
Steer, A. (2023, February 28). Scabies [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 10, 2024, from https://doi.org/10.69645/GYCX7922.Export Citation (RIS)
Publication History
Financial Disclosures
- There are no commercial/financial matters to disclose.
HSTalks is pleased to grant unrestricted complimentary access to all lectures in the series Neglected Tropical Diseases. Persons not at a subscribing institution should sign up for a personal account.
Other Talks in the Series: Neglected Tropical Diseases
Transcript
Please wait while the transcript is being prepared...
0:00
This episode of HS
talks is on scabies.
My name is Professor
Andrew Steer of
the Murdoch Children's
Research Institute,
the University of Melbourne and
the Royal Children's Hospital
Melbourne in Australia.
0:14
As an overview of
my presentation,
I'll be tackling 13
different areas and
we'll move through those
during the course of
the presentation.
0:24
Scabies is an ancient disease,
it was first apparently
described in
1687 by two Italian physicians,
and one of them,
Giovan Cosimo Bonomo,
described scabies as this.
"I quickly found an
itchy person and asking
him where he felt the greatest
and most acute itching,
he pointed to a great
many little pustules
not yet scabbed over,
of which picking out one with
a very fine needle and
squeezing it from a thin water,
I took out a very
small white globule
scarcely discernible.
Observing this
with a microscope,
I found it to be a very
minute living creature,
in shape resembling a
tortoise of whitish color,
a little dark upon the back
with some thin and long hairs,
of nimble motion with 6 feet,
a sharp head with
two little horns at
the end of the snout",
and thus scabies was
first described.
1:18
Scabies biology, sacroptes
scabiei var hominis,
a variety hominis is the
cause of human scabies.
There are other varieties
of scabies that
do cause disease in
animals other than humans.
But today, we're going to
be focusing on the hominis.
The mites is microscopics,
you cannot see it
with the naked eye.
Females are around 0.3 to 0.4
millimeter long and 0.25
to 0.35 millimeters wide.
Males a smaller, less than
half the size of the female.