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0:00
Hi. My name is Vineet Kumar Rai.
I am an associate professor
in Pharmacy Discipline
and Head of the Department
of Pharmaceutics
at ISF College of
Pharmacy, Moga, Punjab.
The subject of this lecture
is oral drug delivery.
The focus is on the oral route
for both local and systemic uses.
0:20
This slide shows an
outline of the lecture.
After a brief introduction,
the significant advantages,
disadvantages and
challenges associated
with the oral route of
administration will be discussed.
It further includes anatomy of
the gastrointestinal tract,
its components, functions,
different barriers against
oral drug delivery,
factors to be considered
for oral administration
and most suitable dosage forms.
0:48
The introduction slide shows
the paramount importance
of drug delivery.
As far as the
current market share
of the oral drug delivery
system is concerned,
it is about 90%.
At the same time, it
covers nearly 84% of
the best-selling
pharmaceutical products
with a value of 35
billion US dollars.
This market is growing
at a phenomenal rate
that is more than 10% annually.
Hence, these factors prove
the oral route is the
most preferred route
for drug administration.
Why is it so?
1:22
It is because the oral route is
well-known for its
painless administration.
It allows easy administration
by the patient themselves,
since taking anything
orally is convenient.
It offers great
patient compliance.
Furthermore, it is a
cost-effective method
compared with the
other routes and
it doesn't require any
specific or sterile condition
during dosage form development
and administration.
We all practice
self-administration from our mouth
and it doesn't require any
expert for the same purpose.
Additionally, the lumen of
the gastrointestinal tract
offers an enormous
surface area for
drug absorption through
the entire length
of the gastrointestinal tract.
The formulation scientists
always have flexibility
in designing different
dosage forms
for the administration of
the drugs by oral routes.
Therefore, every dosage form
has been developed to date,
ranging from liquid dosage
forms to solid dosage forms.
Moreover, it offers great ease
in scale-up and
large-scale manufacturing.
