The management of chronic liver disease, including transplantation 2

Published on September 30, 2021   21 min

Other Talks in the Therapeutic Area: Immunology & Inflammation

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We'll move on to listing for liver transplantation.
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Currently, there is no uniform organ allocation system within the world or countries, it is usually center-driven. However, in the United States, it is driven by the government, to where currently, the allocation system has evolved from the model for end-stage liver disease to MELD with sodium. This is a status system, where the highest scorer on the MELD score is the individual who is chosen as the recipient for liver transplantation. MELD exception points are now under the national review board, rather than regional review boards. Each center will be allocated a mean MELD score at that center, minus their three points. Donation for transplantation includes donation after brain death, donation after circulatory death (DCD donors), and living donation (liver donation). Extended donor criteria include those individuals who are older than 65, who have marked steatosis within the graft, who have a DCD donor, if the donor has an infection at time of transplantation donation, some specific neurologic tumors, and high-risk behaviors, such as those individuals who have opiate addictions and IV drug use.
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The management of chronic liver disease, including transplantation 2

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