McCashland, T.M. (2021, September 30). The management of chronic liver disease, including transplantation 1 [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved February 24, 2024, from https://hstalks.com/bs/4786/.
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Published on September 30, 2021
Prof. Timothy M. McCashland has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
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Hello, my name is Tim McCashland, I'm Professor of Medicine, and Director ofLiver Transplant and Hepatology, at the University of Nebraska Medical Center.Today I would like to talk about the management of other aspects of chronicliver disease, including liver transplantation.
The outline for today's talk includes:management of common complications associated with end-stage liver disease;preparation for evaluation and listing for liver transplantation;listing criteria for liver transplantation;management of common medical conditions after transplantation.First, we'll start with management of common complicationsassociated with end-stage liver disease.
The number one complication of end-stage liver disease is ascites.There is a 50% 10-year probability of accumulation of ascitesin somebody with end-stage liver disease.It's a harbinger of poor prognosis, with 50% mortality within two years of diagnosis,for patients who have a large amount of ascites.Ascites can be graded from grade 1 to 3, based upon the volume of the ascites,with ultrasound diagnosis for grade 1, grade 2 with moderate abdominal distention,and grade 3 with tense ascites and significant abdominal discomfort.Typically speaking, you require at least 1,500 ml of ascites to be detected by physical examination.Ascites typically is associated with a clear yellow consistency in color.If the ascites - on tapping - is bloody in appearance,the hematocrit should be greater than 0.5 percent.