Hair & hair growth

Published on May 4, 2014   57 min
Hello, I'm Desmond Tobin, Director of the Center for Skin Sciences at the University of Bradford. Over the next hour or so I would like to discuss with you the fundamentals of the hair follicle and how it produces its main secreted product, the hair fiber.
My talk will be structured as follows. I will give a little context on the biological value of hair as the major appendage of the skin. Then I will describe how the hair follicle coordinates several distinct histological cell types, and can be viewed therefore as a mini organ. From there I will briefly discuss the development of the hair follicle, first during embryogenesis. Once developed the hair follicle then enters a lifelong cyclical activity, a feature that makes it unique in the mammalian body. Much of the recent biomedical interest in the hair follicle stems from its significant regenerative capacity. So I will talk briefly about its complement of stem cells. Note the general area of stem cells will be a feature of its own series in the Henry Stewart Talks collection. Another major development in hair follicle science over the last 10 years has been the rather unexpected inclusion of the hair follicle in the nuero-endocrine family of body tissues. This will be covered only briefly here. However, one of the hair follicle traits that is tightly connected to the neuro-endocrine system is its pigmentation system. And this will be covered here. Finally, I will conclude the talk with an overview of a couple of the more common hair growth disorders, alopecia areata and common baldness.