Atopic eczema/atopic dermatitis

Published on September 29, 2016   49 min

Other Talks in the Series: Allergy - From Basics to Clinic

Other Talks in the Series: Skin Biology

Hello, I'm Michael Ardern-Jones, Associate Professor of Dermatology and Clinical Consultant Dermatologist at the University of Southampton. And today I'm going to talk to you about Atopic Eczema. In this title slide reminds me to have emphasize that the term Atopic Eczema is synonymous with the Atopic Dermatitis. The two are completely interchangeable and if I use atopic eczema throughout subsequent slides then you could also replace that with atopic dermatitis.
Atopic eczema is one of variety of different eczemas and I've listed here some different variants of eczema which I'm not going to focus on this presentation, instead I'm going to talk about atopic eczema which is characterized by an itchy, chronically relapsing, inflammatory skin condition that is much more prominent in childhood than in adulthood.
I'm going to talk to you about epidemiology, diagnostic criteria and clinical features, co-morbidities, genetics, immunology, allergy and current management, and then I'm going to move on to future management of the disease.
Epidemiology of atopic dermatitis has been studied for a long time and one of the most important studies has been the international study on asthma and allergy in childhood which looked at the prevalence of allergies, including eczema, in 106 countries. And this study was able to undertake a global prevalence measurement of atopic eczema and you can see here that although there was a wide range of prevalence in atopic eczema in different countries that actually this is a common disease in children. The UK as you can see it lies at the upper end of the prevalence range and this is reflected in the health demands in our country. A recent systematic review of prevalence studies has shown that lifetime prevalence of atopic eczema is approximately 20% in Western countries and that this is in fact increasing year on year. A recent study looked at the prevalence in different age groups of children and you can see here how majority of atopic eczema arises in the first year of life. Adults atopic eczema is far less common and affects one to three percent of adults.