Cutaneous extracellular matrix

Published on May 4, 2014   26 min
0:00
Hello. My name is Hironobu Fujiwara. I am currently studying at the RIKEN Center for Developmental Biology in Kobe, Japan. Today I'd like to talk about several of the extracellular matrices, ECM in mammalian skin.
0:18
Here is outline of my talk. First, I'll explain the general importance and function of cell-ECM interactions. Second, I'll talk about the skin ECM, which comprises a basement membrane and interstitial matrix. Third, skin ECM heterogeneity. Fourth, ECM-integrin interactions in epidermal stem cell regulation. And fifth, non-cell-autonomous functions of the skin ECM. I'll then move on to the role of the ECM in aging and associated pathological conditions, followed by perspectives.
0:56
First, I'll talk about the general importance and function of cell-ECM interactions.