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Printable Handouts
Navigable Slide Index
- Introduction
- Lecture contents
- Steptoe and Edwards
- The era of ART
- History of IVF (1)
- History of IVF (2)
- Requirements for conception
- Menstrual cycle
- Embryo development and implantation
- Causes of infertility
- ART – first IVF
- Ovarian stimulation
- Ovarian stimulation – gonadotropins
- Gonadotropins
- Human menopausal gonadotrophins
- Controlled ovarian stimulation in IVF
- Ovarian stimulation – role of GnRH
- GnRH agonists and antagonists
- GnRH agonists and antagonists: mechanism of action
- 1987 GnRH-agonist treatment protocol
- 1998 GnRH-antagonist treatment protocol
- Ovarian stimulation - gonadotropins
- Aspiration
- Cumulus oocyte complex
- Fertilization: conventional IVF
- Fertilization: intra cytoplasmic sperm injection (ICSI) (1)
- Fertilization: intra cytoplasmic sperm injection (ICSI) (2)
- Testicular sperm – severe male factor infertility
- ICSI – use of a single sperm
- Embryo development
- The embryo
- The endometrium
- Embryo transfer
- Gamete/embryo freezing
- Freezing techniques (1)
- Freezing techniques (2)
- Freezing and storing
- The genetic revolution
- Pre-gestational testing (former PGD / PGS)
- PGT – the biopsy
- Embryo biopsy
- Genetic testing
- Pre-gestational testing
- Uterine infertility – gestational surrogacy
- Indications for gestational surrogacy
- Surrogacy
- Uterine transplantation
- Livebirth after uterine transplantation
- IVF – regenerative medicine
- Regenerative medicine
- Nuclear Transfer “Three-parent embryo”
- Thank you
Topics Covered
- Assisted reproductive technology
- Gamete/embryo freezing
- Pre-gestational testing
- Surrogacy and uterine transplantation
- Embryonic stem cells, nuclear transfer and cell therapy
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Imbar, T. (2022, June 30). Assisted reproductive technology (ART) [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 23, 2024, from https://doi.org/10.69645/MDUQ4640.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Tal Imbar has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Other Talks in the Series: The Female Reproductive System: from Basic Science to Fertility Treatments
Transcript
Please wait while the transcript is being prepared...
0:00
My name is Tal Imbar,
and I'm a medical doctor,
the Head of the Fertility
Preservation Service in
the In Vitro Fertilization
Unit of the Hadassah Hospital,
which is the Hebrew
University Medical Center.
I want to talk to you about
the Assisted Reproductive
Technology, ART,
in vitro fertilization,
intracytoplasmic sperm injection
and all other things that
correlate to this
new technology.
0:31
The lecture will include
an introduction about
the history of IVF
and then a detailed explanation
about assisted
reproduction technologies.
I will talk about the ovarian
stimulation, its goals,
and how it achieves the
fertilization of the oocyte
by the sperm and
then embryo transfer
and implantation.
I will talk about gamete
and embryo freezing and
our new freezing technologies
and I'll also talk about
other technologies
and the other revolution that
happens due to our
IVF abilities,
mainly the genetic revolution
and the pre-gestational testing
and the surrogacy and
uterine transplantation.
In the end,
I will mention some of
the embryonic stem cells,
nuclear transfer and
cellular therapy
being applied in the
infertility clinic these days.
1:27
41 years ago,
this short letter in
the Lancet Journal
was the peak of years of
research in reproduction.
The scientific paper
was very short,
in the form of a
public announcement,
without any details about
how the IVF was really done.
Lesley Brown and her
husband John had failed to
conceive naturally
throughout the nine years
of their continuous marriage.
Lesley Brown had
bilateral tubal blocks.
Dr. Robert Edwards and
Mr. Patrick Steptoe
did a laparoscopic oocyte
retrieval during a natural cycle
and used the husband's
sperm to fertilize
their retrieved oocyte
in the lab in a dish.
A few days later,
an 8-cell stage embryo was
placed inside Lesley's
uterine cavity.