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- General Virology
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1. Principles of virology
- Prof. Vincent Racaniello
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2. Antiviral drugs (non-HIV)
- Prof. Megan Shaw
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3. The type I interferon system and viruses
- Dr. Adolfo Garcia-Sastre
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4. Immune responses to viruses
- Prof. Paul Klenerman
- Emerging Pathogens
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5. Emerging or newly discovered viral causes of acute lower respiratory tract infections worldwide
- Dr. Marietjie Venter
- Mrs. Orienka Hellferscee
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6. Emerging respiratory viruses - discoveries between 2001 and 2005
- Prof. Ron Fouchier
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7. Usage of vaccines and therapeutics in public health emergencies 1
- Prof. Gary Kobinger
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8. Usage of vaccines and therapeutics in public health emergencies 2
- Prof. Gary Kobinger
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9. Influenza virus pandemics: past and future
- Prof. Peter Palese
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10. SARS-CoV and other emerging coronaviruses
- Prof. Ralph Baric
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11. Dengue, Zika and Chickungunya viruses
- Prof. Ana Fernandez-Sesma
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12. Biodefense challenges
- Dr. David Franz
- Important Pathogens and their Diseases
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13. Natural history and pathogenesis of herpes virus infections
- Prof. Richard Whitley
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14. Cytomegalovirus biology
- Prof. Domenico Tortorella
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15. Hepatitis C virus: discovery, cure and protection
- Dr. Matthew Evans
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16. Fundamentals of HIV biology
- Prof. Viviana Simon
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17. Measles
- Prof. Diane E. Griffin
- New Frontiers
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20. Viruses as anticancer weapons
- Prof. Roberto Cattaneo
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21. Novel approaches to diagnosis of viral infections
- Prof. W. Ian Lipkin
- Archived Lectures *These may not cover the latest advances in the field
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22. Principles of virology I
- Prof. Richard Condit
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23. Principles of virology II
- Prof. Richard Condit
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24. Complex DNA viruses: herpes virus
- Dr. John Blaho
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25. Adeno-associated viruses (AAV)
- Prof. Kenneth Berns
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26. Poxviruses: smallpox (variola), vaccinia and monkeypox
- Prof. Paula Traktman
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27. Can HPV testing be the sole primary cervical screening modality?
- Prof. Jack Cuzick
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28. From viruses to oncolytics
- Prof. Roberto Cattaneo
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29. Non HIV antivirals
- Prof. Mary Klotman
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30. Gastroenteritis viruses
- Prof. Mary Estes
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31. Biodefense challenges
- Dr. Connie Schmaljohn
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33. The past, present and future of vaccination
- Prof. Stanley Plotkin
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34. Filoviruses
- Dr. Christopher Basler
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35. Bunyaviruses
- Prof. Richard Elliott
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36. The immunobiology of HIV
- Prof. Norman Letvin
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37. Hepatitis C and HCV
- Prof. Stanley Lemon
Printable Handouts
Navigable Slide Index
- Introduction
- Marburg virus history
- Ebola virus history
- Known Ebola virus outbreaks
- Information to family members of Ebola patients
- Genes and gene products
- Filovirus structure
- Ebola virus entry
- Structure of GP
- Filovirus RNA synthesis
- Ebola minigenome with GFP-CAT fusion
- Ebola minigenome assay
- VP40 late domains mediate viral budding
- Ebola virus pathogenesis
- The interferon system (1)
- The interferon system (2)
- delNS1 virus complementation assay
- VP35 protein complements growth of delNS1 virus
- IFN beta-reporter assay of interferon function
- VP35 blocks SeV activation of ISRE-54 promoter
- VP35 inhibits virus-induced IFN-beta expression
- VP24 inhibits IFN alpha/beta-induced signaling?
- EBOV inhibits PY-STAT1 nuclear accumulation
- STAT1 nuclear import
- VP24 interacts with karyopherin alpha 1
- VP24 inhibits interaction of STAT1 with K-alpha-1
- Ebola viruses must be adapted to be lethal in mice
- Interferon-alpha/beta receptor knockout mice
- Genetic changes during mouse adaptation
- Growth in the presence of IFN alpha/beta
- Vaccines
- Vesicular stomatitis virus-based vaccine
- Future directions
Topics Covered
- Filovirus history
- Filovirus genes, proteins and structure
- Filovirus replication cycle
- Evasion of interferon responses by filoviruses
- Filovirus vaccines
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Basler, C. (2007, October 1). Filoviruses [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved March 29, 2023, from https://hstalks.com/bs/357/.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Christopher Basler has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.