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Printable Handouts
Navigable Slide Index
- Introduction
- Part 2 - outline
- National & international surveillance of resistance
- Collecting routine resistance data
- MRSA as percentage of S. aureus bacteraemia
- E. coli from bloodstream infections: turning nasty
- Carbapenem-resistant K. pneumoniae
- Percentage of non-susceptible E. coli
- Two approaches to resistance surveillance
- Major global sentinel surveillances
- Limits of large international sentinel surveys
- Cephalosporin resistance - BSAC surveillance
- ESBL rates in Asia-Pacific Region
- BSACS
- MRSA in bacteraemia
- Relative decline of EMRSA-16 in bacteraemia
- Cephalosporin resistance prevalence
- Piecing data together from many sources
- CTX-M ESBLs worldwide
- ST131 E. coli serotype O25b: a global clone
- Worldwide carbapenemases dissemination
- Information for action & to assess success
- MRSA bacteraemia: England 1990-2013
- Beta-lactam use & resistance in S.pneumoniae
- PCV7 & 13 and invasive pneumococcal disease
- How ery-R pneumococci have changed
- UK ciprofloxacin resistant gonococci
- UK - GRASP surveys
- Summary: resistance surveillance
Topics Covered
- Sets of surveillance data: routine data collection & sentinel surveillances
- Two approaches to resistance surveillance using lab data
- Information for action and to assess success
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Livermore, D. (2016, August 31). National and international surveillance of antibiotic resistance 2 [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 5, 2024, from https://doi.org/10.69645/UFEZ3257.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. David Livermore has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
National and international surveillance of antibiotic resistance 2
A selection of talks on Infectious Diseases
Transcript
Please wait while the transcript is being prepared...
0:00
Hello, I'm Professor David Livermore
of the University of East Anglia
and Public Health England's lead
on surveillance
of antibiotic resistance.
And I wanted to pick up now
in the second part
of this presentation on national
and international surveillance
of antibiotic resistance.
0:23
We're going to look at
some sets of surveillance data,
both routine data collection
and sentinel surveillances.
And also how these systems
can be used to asses the success
and failure
of different interventions
aiming to control resistance.
0:48
Having said all those caveats,
let's now go on
to look at several national
and international
surveillance systems.
See what we can make
of the data,
look at what's good,
look at what we have
to be careful of.
1:05
And one way to do surveillance
nationally or internationally
is to collect
routine susceptibility data.
Up and down the country,
let alone around the world,
millions of susceptibility tests
are done with disks
on automated systems, Vitex,
Phoenix, and such like, everyday.
All those data are out there,
and there is some attempt
to collect them in.
In the United Kingdom,
the Department of Health
has mandatory reporting
of a few types of infections,
bacteraemias due to methicillin
resistance Staph. aureus.
E. coli, also nowadays
to Staph. aureus in general.
And for a while, to outline
a few slides ago,
the Department of Health
also collected
mandatorily information
on bacteraemias,
due to vancomycin
resistance enterococci.
All that depends on the
hospitals own results.
Public Health England
also seeks to collect in,
onto a voluntary scheme,
data for all bacteraemias.
Hospitals are asked
to report all the patients
who've had a bacteraemia,
the pathogens,
and the susceptibility results
that were obtained.
And that system, it's now called
second generation
surveillance system,
is being expanded so that
it will seek
all susceptibility data
for all pathogens isolated
at least in England.
Internationally, or at least across
the European Union,
there's a system called EARS-net
which looks at selected
drug-bug combinations,
in bacteraemia
across a representative range
of hospitals in the country,
essentially about one site
of million head of population.