Evidence-based treatment of pyelonephritis and other urinary tract infections

Published on September 28, 2023   34 min

A selection of talks on Infectious Diseases

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Thanks for having me here. My name is Dimitri Drekonja. I'm going to be speaking on evidence-based treatments of pyelonephritis, and other urinary tract infections. I'm the Chief of Infectious Diseases here at the Minneapolis VA Health Care System. Also, Associate Professor of Medicine at the University of Minnesota. I come to this from the perspective of someone who conducts clinical trials, particularly in the area of urinary tract infections trying to find really the best evidence-based for treating patients that we see clinically.
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Briefly, for disclosures only some grant funding from the Department of Veterans Affairs, from VA Merit Review, and from the VA Cooperative Studies Program. No pharmaceutical affiliations.
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This is the outline of what's going to be covered here. First, going to go through some background in epidemiology of urinary tract infections. Then we'll go into what's in the name. Really, not everything that is put under the moniker of UTI is the same. I think it's important to use precise language because when we use that catch-all term, we lose any of the specificity that the different syndromes have and there's quite a bit of prognostic information and treatment information in there. The specific clinical syndromes that we'll go over are cystitis, AKA lower UTI. Then, moving on to pyelonephritis, which also gets the number of upper UTIs. Then, we'll move into febrile UTI, which has various sub-classifications including a couple of important ones that I have here, urosepsis, and emphysematous pyelonephritis. Something that I'll explain what the acronym means there. But we'll call it BPCUS for now. Then, moving onto asymptomatic bacteriuria. I will briefly mention prostatitis, which really deserves its own lecture in its own right. Finally, going to close out with a term that vexes everybody in the UTI field. That is the term complicated. What exactly is a complicated UTI? What do we mean by that? Do people mean the same things when they use that term? Then, we'll summarize the take-home points and hopefully, leave with a good overall understanding.

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Evidence-based treatment of pyelonephritis and other urinary tract infections

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