The cytogenetics of childhood acute leukemia

Published on May 31, 2016   52 min

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Other Talks in the Series: Cancer Genetics

0:00
My name is Susana Raimondi. I work at St. Jude Children's Research Hospital. I'm the director of the Cytogenetics Laboratory, and the presentation today will be about the cytogenetics of childhood acute leukemias.
0:17
Regarding the topic today, the molecular changes occur at the chromosome level, at the gene level, or DNA sequences. A full range of genetic abnormalities is indicative of cancer, but many of the chromosomal alterations observed by conventional cytogenetics alone do not induce leukemia. Sometimes, there are no obvious chromosomal alterations. And some microscopic genetics alterations may be of leukemogenic/actionable events.
0:54
Regarding the cytogenetics of acute lymphoblastic leukemia,