Metabolic communication in development and control of obesity 1

Published on January 31, 2016   43 min

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Hello, my name is Elaine Holmes. I'm Professor of Biological Chemistry at Imperial College, London. And today, I'm going to talk about the metabolic communication in the development and control of obesity.
0:13
If we look at the CDC statistics for obesity in America, what you can see is that back in 2010, already a lot of the southern half of the United States were in the situation where over 30 percent of the population had a BMI of 30 or greater, meaning that they were clinically obese. And if you look at this spread over successive years, it seems to develop a little like an infection. Now, diet obviously plays a big role and also genetics. And obesity is linked, we know, to a lot of diseases, a lot of comorbidities. So, for example, in the lower panel, if you look at the prediction, by 2023 in the States for various diseases, if we look at type 2 diabetes, you can see that we're expecting 54 percent of the population to have developed type 2 diabetes by 2023. So this is a big health problem, a big socioeconomic problem. We know that obesity is also linked to the developmental or risk of cancer, and these are not just cancers you'd expect to be linked to obesity such as liver cancer, but we're also seeing cancers like prostate cancer and leukemia, there are also rising in association with obesity.
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Metabolic communication in development and control of obesity 1

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