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Printable Handouts
Navigable Slide Index
- Introduction
- Research is essential to underpin precision medicine
- What is personalised medicine?
- Personalised medicine
- Biomarkers guidance treatment for obesity
- Predict responses to weight management
- Personalized nutrition
- What about genetics?
- Strong genetics effect
- Modify surgical procedures for particular patients
- Obesity is complex
- Many types of obesity
Topics Covered
- What is personalised medicine
- Using biomarkers to guide treatment of obesity
- Personalised nutrition
- Personalised of surgical procedures
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Blakemore, A. (2016, June 30). Towards personalised medicine in obesity [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 6, 2024, from https://doi.org/10.69645/MPWR3249.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Alexandra Blakemore has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Other Talks in the Series: Obesity: Science, Medicine and Society
Transcript
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0:00
Hello,
and welcome to the final lecture
in the series Obesity,
Science, Medicine and Society.
I'm Professor Alex Blakemore
and I'm one of the two editors
of this series.
I'm going to give
a few concluding remarks
and talk a little bit
about prospects
for future treatment of obesity.
0:21
Series so far has provided
a wonderful
whistle-stop tour of obesity,
but in each topic
there is still so much to learn,
and lots of questions
come to my mind
when watching the lectures.
I'm sure they do for you too,
so talking about psychology,
I'm interested
in what mechanisms
underlie the relationship
between emotion-handling
and eating behavior?
How does that work?
And what psychological
interventions
would be most
effective long-term?
'Cause it's not too difficult
to get people
to lose weight in the short term
but maintaining that weight loss
is a real challenge.
In the biology, what's exactly
is the relationship
between the gut microbes
and the host body?
How do rare genetic variants
and the SNPs interact?
We know that both involved
in predisposing to obesity,
but how do they work together?
And what are the key
sex differences
in obesity pathogenesis?
Why is it so much
more common in women
than in males?
And what about
adipose tissue dysfunction?
Are there ways that we can
cause our white fat
to become beige or brown fat?
In terms of treating obesity,
what can we do about
interventions?
What kind of public health
approaches can we apply
that would actually work?
Can we provide
non-surgical therapies
by mimicking some of the effects
of bariatric surgery
and after surgery
or after weight loss,
again we come back
to the question,
how can we sustain
weight loss long-term?
Research in all these fields
is ongoing
and is essential to allow us
to develop methods
to personalize treatments
for those with severe obesity.