Hello and a very warm welcome from Charité here in Berlin.
My name is Marcus Maurer and I'm very happy that you have the time to join us
in our review of "Chronic Spontaneous and Chronic Inducible Urticaria".
What we'll be doing over the next 60 minutes is to discuss new data on chronic urticaria.
All of this of clinical relevance,
we will start with looking at the burden of disease,
the epidemiology, and also the state of how patients are treated in clinical practice.
We will then talk about the diagnostic workup and end up with
therapeutic approaches for patients with
chronic spontaneous and chronic inducible urticaria.
Chronic urticaria is a disease characterized by
itchy wheals and angioedema or angioedema.
It is important to understand that these two signs and symptoms,
wheals and angioedema can be present in patients both of
them or just wheals or just angioedema.
In our current classification of chronic urticaria,
we distinguish between spontaneous urticaria and inducible urticaria.
There is a group of inducible urticarias which are then subgrouped again,
you can see this on the right side of the slide,
into physical urticarias and other inducible urticarias.
What is common to all inducible urticaria is that there is a specific,
a definite trigger that needs to be there in order for wheals,
angioedema, or both to happen.
When this trigger, for example,
cold in cold urticaria is not present there are no wheals,
there is no angioedema.
But every time this trigger is present,
patients will suffer the consequences.
In contrast, spontaneous urticaria is characterized
by wheals and angioedema that come seemingly out of the blue,
and there is no definite trigger that can be linked to the signs and symptoms.