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1. Introduction
2. Definition
3. Complications associated with SSc
4. Sclerodactyly
5. Raynaud’s phenomenon
6. Dilated capillaries
7. Calcinosis
8. Telangiectasias
9. Interstitial lung disease
10. Epidemiology
11. Pediatric scleroderma
12. Genetics
13. The disease process in systemic sclerosis
14. Disease pathogenesis
15. Humoral immune system alterations
16. Tissue inflammation in early disease
17. Cellular immune response
18. Fibrosis
19. Molecular mechanisms in SSc
20. Systemic sclerosis classification criteria
21. Early diagnosis of systemic sclerosis
22. Screening and diagnosis
23. Biomarkers
24. Clinical consequences: fibrosis
25. Skin Fibrosis
26. The modified Rodnan Skin Score (mRSS)
27. Skin thickness progression rate
28. Effectiveness of therapies
29. Immunomodulatory therapies
30. Antifibrotic therapies
31. Targeted immunosuppression
32. Disease modification
33. New targeted therapies for SSc fibrosis

Topics Covered

• Complications associated with systemic sclerosis
• The disease process in systemic sclerosis
• Disease pathogenesis
• Humoral immune system alterations
• Fibrosis
• Molecular mechanisms in systemic sclerosis
• Systemic sclerosis classification criteria
• Biomarkers
• The modified Rodnan Skin Score
• Skin thickness progression rate
• Effectiveness of therapies
• New targeted therapies for SSc fibrosis

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Categories:

• Clinical Medicine
• Immunology

Therapeutic Areas:

• Dermatology
• Immunology & Inflammation

Talk Citation

Publication History

• Published on September 27, 2018

Financial Disclosures

• Prof. Chris Derk has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.