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Printable Handouts
Navigable Slide Index
- Introduction
- Vaccines will address challenges of 21st century
- Aging society
- Causes of increased average life expectancy
- Increased life expectancy due to less diseases
- Pasteur started the greatest revolution in history
- Life expectancy is growing beyond prediction
- HIV - example of the impact of infectious diseases
- Vaccination is the most effective treatment
- Future vaccination will be for all ages
- New tech. increased vaccine targets and safety
- Safety of vaccines increased in the 21st century
- Vaccines developed following Pasteur principles
- Safety concerns about crude preparations
- Vaccines with safety concerns were discontinued
- Increased vaccine safety
- Types of novel technologies of vaccines
- Meningococcal disease (1)
- Meningococcal disease (2)
- N. meningitidis has many serotypes
- Glycoconjugation improves the immunogenicity
- Conjugate vaccines for meningococcus C
- A self antigen cannot be used for vaccination
- No success for developing a vaccine for MenB
- OMV was successful to eliminate epidemic in NZ
- Genomics and "reverse vaccinology"
- 3 main antigens included in a vaccine
- A vaccine able to induce antibodies in vitro
- Reverse vaccinology improves targeting
- Vaccines are the response to antibiotic resistance
- Many cancers can be prevented
- New vaccines will address health of aging society
- Emerging infections
- The evolution of the H1 Hemagglutinin sequence
- A vaccine against avian influenza, H5N1
- MF59: established adjuvant in a licensed vaccine
- Vaccinating with clade 1 H5N1 after clade 0
- Memory T cells induced first, B are more abundant
- The H5N1 pandemic prepared us to face H1N1
- Poverty
- Vaccines to address poverty
- Addressing the gaps in vaccine development
- Novartis Vaccines Institute for Global Health
- Combination conjugate Salmonella vaccines
- Vaccines in the 21st century
Topics Covered
- Major health challenges of the 21st Century
- Causes of increased life expectancy: conquest of infectious diseases
- Life expectancy is growing beyond prediction
- New technologies in the last 30 years
- Safety of vaccines
- Meningococcal disease
- Vaccines for Meningococcus C
- Meningococcus B
- Reverse vaccinology allows us to target many pathogens that were difficult or impossible before
- Prevention of cancers
- Vaccination and our aging society
- H5N1 vaccine
- Vaccines to address poverty
- Novartis Vaccines Institute for Global Health
Links
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Talk Citation
Rappuoli, R. (2011, August 31). Vaccines: a health insurance of the 21st century [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 11, 2024, from https://doi.org/10.69645/CUIP6899.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Rino Rappuoli has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.