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Interviewer: Today, I'm
interviewing Dr. Douglas Anderson,
Director of Pancreas Transplantation at
the University of Alabama at Birmingham,
that is UAB Medicine,
about the recent xenotransplant of a
porcine kidney into a human decedent.
The experiment is reported
in a paper published in
the American Journal of Transplantation
on 28th of January 2022.
A link to the paper
accompanies this interview,
and it is anticipated that listeners
have at least read the abstract,
before accessing this interview.
Dr. Anderson, thank you for sparing
the time for this interview.
To start, what do you believe has
been established by this experiment?
Dr. Anderson: Well, thank
you for the invitation.
I think this was a
critical first step
towards showing that
genetically engineered pigs can
potentially become a clinical reality.
There have been numerous
papers and mounds of research
over many years by many
individuals at many institutions,
searching for a way to make
As we all know,
there is a desperate shortage of
available organs for transplantation,
and it's long been felt that animals represented
a potential source to overcome that shortage.
But the barriers to
making that work,
immunologic and otherwise,
have always been quite
challenging to overcome.