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Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- Time is an essential ingredient in nature's pattern generator
- What enamel looks like in transverse section
- What happens if you describe lots of ringss on lots of trees?
- A baby tooth
- This is a curiosity
- Enamel incremental anatomy
- Long period rhythm in enamel?
- Understanding primate life history from enamel development
- The primate life history package
- An example
- Enamel rhythm - what's it all about?
- How about among early and modern humans?
- Multidien enamel rhythms and body size
- Summary of primate enamel repeat intervals and tissue/organ mass
- Lamellae are periodic growth lines in bone
- Primary and secondary lamellae are on the same growth schedule
- The relationship between enamel and bone formation
- The Havers-Halberg oscillation
- The key to a metabolism-mediated life history
- The primate life history package: what is missing?
- Relationship with gestation length
- Relationship with lactation length
- Relation with maximum lifespan
- Relationship with cranial capacity among primates
- Relationship with cranial capacity for early humans
- Relationship with BMR (W)
- Summary or primate enamel repeat intervals and life history
- What mechanisms explain the diversity of life?
- The swine metabolome
- 228 metabolites of high analytical grade
- SUS SCROFA 5-day enamel repeat period
- Cosinor analysis of a circadian rhythm
- The SUS SCROFA 5-day mutlidien metabolome
- A selection of 22 metabolites for animal #17 (23:00)
- The gene network describing the SUS SCROFA 5-day multidien metabolome
- The gene network describing the SUS SCROFA 5-day multidien sncRNA-OME
- The complete SUS SCROFA cross-correlation matrix
- Correlation between SUS SCROFA metabolites and sncRNAs
- The primate life history package
- Enamel striae of Retizus and modern human body size
- Multidien rhythms in hard tissue biology
- The significance of lamellae widths
- Time to fall asleep?
- Primary lamellar bone from the midshaft femur
- 66ZN/88SR concentrations of primary lamellar bone
- Acknowledgements
- Bibliography
Topics Covered
- Human tooth enamel forms growth increments
- Stria of Retzius and the enamel repeat interval
- The repeat interval varies across the order Primates and correlates with different characteristics
- Havers-Halberg Oscillation (HHO)
- Metabolomics and genomics research on the HHO
Talk Citation
Bromage, T. (2021, February 25). Hard tissue biology in human health and evolution: life history and chronobiology [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 14, 2024, from https://doi.org/10.69645/OCZG9594.Export Citation (RIS)
Publication History
Financial Disclosures
- There are no commercial/financial matters to disclose.
Hard tissue biology in human health and evolution: life history and chronobiology
Published on February 25, 2021
26 min
A selection of talks on Clinical Practice
Transcript
Please wait while the transcript is being prepared...
0:00
My name is Tim Bromage of the New York University College of Dentistry.
In this presentation, I'll provide
further topics within the general theme of hard tissue biology
in human health and evolution.
0:15
There are several aspects of hard tissue biology within the health sciences,
that have been the explicit focus of attention in human evolutionary biology.
These include enamel and tooth biology,
bone biology, craniofacial biology,
and - as the focus in this presentation -
applications in both the medical and human evolutionary sciences
that concern life history and chronobiology.
0:43
Nature abounds with pattern.
One category of patterns is composed of what are called 'recording structures'.
These are typically layers that represent formation over some discrete period of time.
For instance, the annual rings of trees,
tidal variation in seashells,
incremental growth of fish scales and corals,
fish otoliths, mammalian enamel and bone, layers laid down during agate formation,
seasonal layers in sediment microstratigraphy,
and even the macrostratigraphy of sediments.
At all spatial scales from the micron scale of hard tissue increments,
to the kilometer scale of macrostratigraphy,
nature is giving us clues to how things form.
1:33
If you were to section a human incisor tooth along a plane (as shown on the right),
you would see something similar to that of tree rings.
We know that by examining the widths and characteristics of these rings,
we can say something about the life history of that particular tree.
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