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- General Virology
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1. Principles of virology
- Prof. Vincent Racaniello
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2. The type I interferon system and viruses
- Dr. Adolfo Garcia-Sastre
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3. Immune responses to viruses
- Prof. Paul Klenerman
- Emerging Pathogens
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4. Emerging or newly discovered viral causes of acute lower respiratory tract infections worldwide
- Dr. Marietjie Venter
- Mrs. Orienka Hellferscee
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5. Emerging respiratory viruses - discoveries between 2001 and 2005
- Prof. Ron Fouchier
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6. Usage of vaccines and therapeutics in public health emergencies 1
- Prof. Gary Kobinger
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7. Usage of vaccines and therapeutics in public health emergencies 2
- Prof. Gary Kobinger
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8. Influenza virus pandemics: past and future
- Prof. Peter Palese
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9. SARS-CoV and other emerging coronaviruses
- Prof. Ralph Baric
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10. Dengue, Zika and Chickungunya viruses
- Prof. Ana Fernandez-Sesma
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11. Paramyxoviruses: biology & pathogenesis
- Prof. Benhur Lee
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12. Antiviral drugs (non-HIV)
- Prof. Megan Shaw
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13. Biodefense challenges
- Dr. David Franz
- Important Pathogens and their Diseases
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14. Natural history and pathogenesis of herpes virus infections
- Prof. Richard Whitley
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15. Cytomegalovirus biology
- Prof. Domenico Tortorella
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16. Hepatitis C virus: discovery, cure and protection
- Dr. Matthew Evans
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17. Fundamentals of HIV biology
- Prof. Viviana Simon
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18. Measles
- Prof. Diane E. Griffin
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19. Monkeypox virus, vaccines, and therapeutics
- Prof. Rachel Roper
- New Frontiers
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22. Viruses as anticancer weapons
- Prof. Roberto Cattaneo
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23. Novel approaches to diagnosis of viral infections
- Prof. W. Ian Lipkin
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24. The Global Virus Network: collaboration to address pandemic and regional threats
- Prof. Sten H. Vermund
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25. Elite controllers of HIV: from discovery to future therapies
- Prof. Bruce Walker
- Archived Lectures *These may not cover the latest advances in the field
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26. Principles of virology I
- Prof. Richard Condit
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27. Principles of virology II
- Prof. Richard Condit
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28. Complex DNA viruses: herpes virus
- Dr. John Blaho
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29. Adeno-associated viruses (AAV)
- Prof. Kenneth Berns
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30. Poxviruses: smallpox (variola), vaccinia and monkeypox
- Prof. Paula Traktman
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31. Can HPV testing be the sole primary cervical screening modality?
- Prof. Jack Cuzick
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32. From viruses to oncolytics
- Prof. Roberto Cattaneo
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33. Non HIV antivirals
- Prof. Mary Klotman
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34. Gastroenteritis viruses
- Prof. Mary Estes
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35. Biodefense challenges
- Dr. Connie Schmaljohn
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37. The past, present and future of vaccination
- Prof. Stanley Plotkin
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38. Filoviruses
- Dr. Christopher Basler
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39. Bunyaviruses
- Prof. Richard Elliott
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40. The immunobiology of HIV
- Prof. Norman Letvin
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41. Hepatitis C and HCV
- Prof. Stanley Lemon
Printable Handouts
Navigable Slide Index
- Introduction
- Arboviruses (arthropod borne)
- Flavivirus classification (1)
- Flavivirus classification (2)
- Dengue virus transmission
- Dengue virus background
- Global burden of Dengue
- Control efforts: vector control
- Control efforts: egg-laying habitats
- Distribution of Aedes aegypti in the americas
- Dengue disease
- Dengue infection: immune response
- Dengue diagnostics and prevention
- Antibody mediated enhancement (ADE)
- ADE
- Dengue virus
- Flavivirus life cycle
- DENV replicates in vesicles (1)
- DENV replicates in vesicles (2)
- DENV polyprotein processing
- DENV innate immune
- Dengue virus 2 E protein
- Concerns about DENV vaccines
- Dengue vaccine development (1)
- Dengue vaccine development (2)
- Zika virus
- Zika virus: a case study in arboviral emergence
- Phlogeny of flaviviruses and Zika virus
- Zika disease symptoms
- Zika virus transmission
- Zika virus and microcephaly
- Zika virus and Guillain-barre
- Diagnostic challenges
- Open questions
- Zika virus pathogenesis
- Alphaviruses of human health interest
- Chikungunya epidemiology
- Chikungunya virus transmission
- Chikungunya virus (CHIKV)
- Take home messages
Topics Covered
- Arbovirus classification
- Flaviviruses
- Dengue virus transmission
- Antibody mediated enhancement
- Mosquito control
- Dengue infections
- Global burden of dengue
- Dengue virus replication and polyprotein processing
- Innate immune evasion by dengue virus
- Dengue vaccine development
- Zika virus and disease
- Chikungunya epidemiology
- Chikungunya virus
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Fernandez-Sesma, A. (2018, January 31). Dengue, Zika and Chickungunya viruses [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 10, 2024, from https://doi.org/10.69645/HEUR2032.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Ana Fernandez-Sesma has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A selection of talks on Immunology
Transcript
Please wait while the transcript is being prepared...
0:00
Hello. My name is Ana Fernandez-Sesma.
I am a Professor in
the Department of Microbiology at Icahn School of Medicine at Mount Sinai in New York.
And today, I'm going to talk about Dengue, Zika,
and Chickungunya viruses and some important background information,
as well as how we believe they're really able to
deal within our immunity in infected cells.
0:24
First, I want to introduce the concept of
Arboviruses since there's really not a classification,
but its basically referred to
Arthropod Borne viruses and there are several families and genera that belong to
these classification of Arboviruses and it includes
the Togaviridae and Flaviviridae in particular.
And today, we're going to talk about Alphaviruses,
which include different viruses such as
Equine Eastern Encephalitis, Western Equine Encephalitis,
and Venezuelan Eastern Encephalitis that as the name indicates cause encephalitis,
but also includes the infamous virus,
Chickungunya virus that has caused some epidemics in the recent years,
and that can cause febrile disease,
and chronic arthritis in humans.
Then it also includes a family of
Flaviviridae that are all both, Togaviridae and Flaviviridae,
at single strand positive RNA viruses and
the Flaviviruses includes several known pathogens of humans such as West Nile virus,
Japanese Encephalitis, St. Louis Encephalitis that they are causing encephalitis,
then yellow fever virus that cause liver disease,
and also Dengue, and Zika viruses.
Dengue is most known for causing these febrile disease and
Dengue hemorrhagic fever and we will talk a little bit in detail about these virus.
And then Zika virus has been more notorious in the last year because it caused
febrile disease. It had
this severe association of fetal brain damage in infected pregnant women.