My name is Anisur Rahman,
and I'm a Professor of Rheumatology at University College London.
I'm going to be talking about systemic lupus erythematosus,
an autoimmune disease which I study and treat in my clinic.
I have no financial disclosures.
So what is SLE?
It's an autoimmune rheumatic disease and it's a very rare disease.
The recent data shows that it's prevalence in the United Kingdom is about 1 in 1,000.
It's far common in women than it is in men,
with the sex ratio being about nine to one,
and it's more common in some ethnic groups,
particularly African and Caribbean people.
SLE is truly systemic.
It can affect any organ or system in the body.
But, the most common effects are on the skin,
the joints, and the hair,
whereas the most severe effects are on the kidney,
the central nervous system, and the blood.
During this talk, I'm going to cover the following topics:
let's see the clinical features of the disease, the current therapy,
the way we manage lupus now,
and new therapies which have arisen over
the last 10 years as a result of better understanding of the pathogenesis of lupus.