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Printable Handouts
Navigable Slide Index
- Introduction
- Overview
- Sjogren’s disease (1)
- Sjogren’s disease (2)
- Sjogren’s associations
- Epidemiology (1)
- Epidemiology (2)
- Incidence
- Etiology and pathogenesis (1)
- Etiology and pathogenesis (2)
- Pathogenesis: innate and adaptive immunity
- Pathogenesis: auto-antibodies
- SSA (Ro) & SSB (La) disease associated Ab's
- Pathogenesis: role of immune complexes
- Pathogenesis: cytokines
- Genetics
- Etiology and pathogenesis: more data
- Neuro - immune interface
- Channelopathies
- Exocrine gland dysfunction
- Diagnosis
- Classification criteria
- Early detection
Topics Covered
- Sjogren's disease: epidemiology
- Incidence
- Etiology & pathogenesis
- Genetics
- The neuro-immune interface
- Channelopathies
- Exocrine gland dysfunction
- Diagnosis
- Classification criteria
- Detection
Talk Citation
Carteron, N. (2016, October 31). Sjogren’s disease - epidemiology, etiology, pathogenesis & diagnosis [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 27, 2024, from https://doi.org/10.69645/MMCF2725.Export Citation (RIS)
Publication History
Financial Disclosures
- The speaker is a member of the DMC for Bristol Myers Squibb and a medical reviewer and consultant for Healthline.
Sjogren’s disease - epidemiology, etiology, pathogenesis & diagnosis
A selection of talks on Immunology & Inflammation
Transcript
Please wait while the transcript is being prepared...
0:00
My name is Nancy Carteron.
I'm a Scientist
in San Francisco.
I'm a Senior Consultant
in Rheumatology and Immunology
and an Associate
Clinical Professor
at University California
San Francisco,
here in San Francisco.
Today we're gonna talk about
Sjogren's disease.
0:22
The topics that I would like
to cover include briefly,
introducing the topic,
moving onto epidemiology.
Then we'll focus on etiology
and pathogenesis,
moving on to symptoms
and signs of the disease,
followed by diagnosis.
We'll touch
on some treatment options.
And briefly conclude
with some information
on the prognosis of the disease.
0:50
So Sjogren's is
a serious autoimmune disease.
It was first described
by Henrik Sjogren in 1933,
who was an ophthalmologist.
And even from the first reports,
the hallmark,
which maintains true to today,
is an infiltration
of target exocrine glands
by lymphocytes.
These lymphocytes can infiltrate
a wide range of glands
and target organs
not just the exocrine glands.
And this can include skin,
lung, gastrointestinal,
nervous system tissue,
particularly the ganglia.
Sjogren's can occur alone
and then is referred
to as primary Sjogren's
or concomitant with
another autoimmune disease,
then referred
to as secondary Sjogren's.
Examples of these
other autoimmune diseases
that commonly can co-associate
with Sjogren's
are rheumatoid arthritis,
primary biliary cirrhosis,
and lupus.