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Printable Handouts
Navigable Slide Index
- Introduction
- Lecture outline
- Bacterial pathogens and major humans diseases
- New bacterial vaccines in clinical development
- Phases of vaccine development
- Principles of vaccine antigen discovery
- Novel vaccines in development: Gram+ pathogens
- Clostridium difficile-associated disease (CDAD)
- CDAD is mediated by toxins
- Challenges in toxoids design & manufacture
- Pfizer’s bivalent toxoid vaccine
- Pipeline of C. difficile vaccines
- C. difficile vaccines in development
Topics Covered
- New bacterial vaccines in clinical development
- Phases of vaccine development
- Principles of vaccine antigen discovery & validation
- Novel vaccines in development for Gram+ pathogens: C. difficile
Links
Series:
Categories:
- Biochemistry
- Cell Biology
- Diseases, Disorders & Treatments
- Immunology
- Microbiology
- Pharmaceutical Sciences
Therapeutic Areas:
Talk Citation
Jansen, K. (2015, September 30). Bacterial vaccines in development 1 [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 7, 2019, from https://hstalks.com/bs/3125/.Publication History
Financial Disclosures
- Dr. Kathrin Jansen, Dr. Jansen is an employee and shareholder of Pfizer Inc
Bacterial vaccines in development 1
Published on September 30, 2015
20 min
You are viewing a talk that is a part of one of our comprehensive courses. Additional learning material: case studies, projects, workshops and recommended reading; multiple choice questions and suggested exam questions with model answers are available on application. Learn more
Other Talks in the Series: Vaccines
Transcript
0:00
DR. KATHRIN U. JANSEN: Hello.
My name is Kathrin Jansen.
I'm a Senior Vice President at
Pfizer, responsible for vaccine
research and development.
Today, I will discuss bacterial
vaccines in development.
0:14
Today's lecture is
intended to give you
a brief overview of
licensed bacterial vaccines,
and some examples of bacterial
vaccines in development,
to discuss key principles
of bacterial vaccine design
and development, to share with you
some insights in the R&D efforts
to develop bacterial vaccines.
And I will be using three examples.
The examples I have chosen are
programs that my colleagues
and I are working on at Pfizer.
So they are real life examples
of bacterial vaccine development.
Specifically, we will touch
on vaccines in development
to protect against
toxin-mediated diseases.
The example is
Clostridium difficile.
We will touch on
vaccines in development
to protect against a
very complex organism.
The example is staphylococcus
aureus, where the disease is
mediated by the bacterium
itself, and the virulence
factors that it expresses.
And finally, we will discuss
recently licenced vaccines
to protect the gram-negative
bacterium, Neisseria
meningitidis serogroup B.