Registration for a live webinar on 'Innovative Vaccines and Viral Pathogenesis: Insights from Recent Monkeypox Research' is now open.
See webinar detailsWe noted you are experiencing viewing problems
-
Check with your IT department that JWPlatform, JWPlayer and Amazon AWS & CloudFront are not being blocked by your network. The relevant domains are *.jwplatform.com, *.jwpsrv.com, *.jwpcdn.com, jwpltx.com, jwpsrv.a.ssl.fastly.net, *.amazonaws.com and *.cloudfront.net. The relevant ports are 80 and 443.
-
Check the following talk links to see which ones work correctly:
Auto Mode
HTTP Progressive Download Send us your results from the above test links at access@hstalks.com and we will contact you with further advice on troubleshooting your viewing problems. -
No luck yet? More tips for troubleshooting viewing issues
-
Contact HST Support access@hstalks.com
-
Please review our troubleshooting guide for tips and advice on resolving your viewing problems.
-
For additional help, please don't hesitate to contact HST support access@hstalks.com
We hope you have enjoyed this limited-length demo
This is a limited length demo talk; you may
login or
review methods of
obtaining more access.
Printable Handouts
Navigable Slide Index
- Introduction
- Evolving immune response
- Interferons
- The antiviral effect of type 1 IFN
- IFNs induce various pathways
- IFN alpha and beta in an infected cell
- Flexibility of IFN induction
- Viral infections
- Activation of immune response in viral infection (1)
- Immunoregulatory effects of type 1 IFN
- Direct antiviral vs. immunoregulatory effects of IFN
- NK cells during viral infections
- NK cells - innate lymphocytes in defense
- Regulation of NK cell responses by IFN and IL12
- Activation of immune response in viral infection (2)
- IFN signaling
- STAT1 in defense against infection
- Evidence of STAT1-independent IFN signaling
- Evidence of STAT3-independent IL-6 signaling
- Type 1 IFN signaling
- Conditioning model for regulating type 1 IFN effects
- STAT regulation mechanisms
- Cell and cytokine responses to LCMV infection
- Examining STAT expression in NK cells
- STAT expression in NK cells
- STAT expression and activation during infection
- Examining STAT responsiveness
- STAT responsiveness to type 1 IFN
- Contributing factors to STAT1 induction
- STAT1 and STAT2 in IFN gamma response
- IFN gamma expression and STAT4 activation
- Blocking IFN gamma induction
- Type 1 IFN receptor association
- Genes and proteins regulating type 1 IFN effects
- Clinical use of IFN
- Acknowledgements
Topics Covered
- Evolving immune response
- Interferons
- Antiviral effects
- IFNalfa/beta induction
- Role of IFNalfa/beta in fighting off viruses and infection
- Activation of immune response cascades during viral challenges
- Immunoregulation
- NK cells during viral infections
- Innate lymphocytes in defense
- Regulation of NK cell responses by IFNalfa/beta and IL-12
- IFN signaling
- STAT1 in defense against infection
- Kinetics of cell and cytokine responses to LCMV infections
- STAT expression in NK cells
- Type 1 IFN receptor association
- Gene expression and protein-protein interactions for regulating type 1 IFN effects
- Interferon treatment
- Interferon ablation
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Biron, C. (2009, June 30). Type I interferons in innate immunity to viral infections [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 12, 2024, from https://doi.org/10.69645/MKTL7276.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Christine Biron has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.