- Models of Investigation
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41 min
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44 min
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38 min
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62 min
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61 min
- Cell Types and Recruitment
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71 min
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51 min
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42 min
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63 min
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25 min
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61 min
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41 min
- Recognition and Signaling
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50 min
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42 min
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39 min
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44 min
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38 min
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41 min
- Modulation of Effector Responses
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22 min
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42 min
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54 min
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39 min
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38 min
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69 min
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42 min
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27 min
- Pathogen-Host Interactions
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46 min
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50 min
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56 min
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53 min
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34 min
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51 min
- Health and Disease
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39 min
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59 min
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33 min
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38 min
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36 min
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54 min
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49 min
- Archived Lectures *These may not cover the latest advances in the field
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73 min
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32 min
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51 min
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39 min
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63 min
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35 min
Topics Covered
- The insect host defense is a multifaceted process
- Systemic anti-microbial response in Drosophila
- NF-kB: a central transactivator in immune responses
- Gene cascade
- The Toll pathway
- Imd pathway mutants are sensitive to bacterial infections
- Toll pathway mutants are sensitive to fungal infections
- TLR family members and their ligands
- The semmelweis (seml) mutation compromises the anti-gram-positive defense
- Structural aspects of PGRPs
- NF-kB activation by Toll and IMD in Drosophila
- Investigating the response of Drosophila to virus infection
- Response to RNA virus infections
- Keeping parasite numbers low: role of the mosquito immune system
- Losses and amplification of Plasmodium in A. gambiae
- Cactus
- ThioEster-containing Protein 1 (TEP1)
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Hoffmann, J. (2009, May 31). The anti-microbial defense of Drosophila: a paradigm for innate immunity [Video file]. In
The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved March 24, 2023, from
https://hstalks.com/bs/1279/.
Export Citation (RIS)
Publication History
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Published on May 31, 2009
Financial Disclosures
- Prof. Jules Hoffmann has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.