Registration for a live webinar on 'Neuroleptic malignant syndrome' is now open.
See webinar detailsWe noted you are experiencing viewing problems
-
Check with your IT department that JWPlatform, JWPlayer and Amazon AWS & CloudFront are not being blocked by your network. The relevant domains are *.jwplatform.com, *.jwpsrv.com, *.jwpcdn.com, jwpltx.com, jwpsrv.a.ssl.fastly.net, *.amazonaws.com and *.cloudfront.net. The relevant ports are 80 and 443.
-
Check the following talk links to see which ones work correctly:
Auto Mode
HTTP Progressive Download Send us your results from the above test links at access@hstalks.com and we will contact you with further advice on troubleshooting your viewing problems. -
No luck yet? More tips for troubleshooting viewing issues
-
Contact HST Support access@hstalks.com
-
Please review our troubleshooting guide for tips and advice on resolving your viewing problems.
-
For additional help, please don't hesitate to contact HST support access@hstalks.com
We hope you have enjoyed this limited-length demo
This is a limited length demo talk; you may
login or
review methods of
obtaining more access.
Printable Handouts
Navigable Slide Index
- Introduction
- Introduction- Prof. George Calin
- Central dogma of molecular oncology
- 13q14.3: one region and two types of genes
- MicroRNA - size doesn't matter
- Small RNAs make a big splash
- How many RNAs are enough for what?
- HE-miRNA mediated control of haematopoiesis
- Mir-155 inhibited generation of colonies
- Alterations of miRNAs are found in all tumor types
- MiR15a and miR16-1 in B-CLL
- Microarray of CLL cells
- MiRNA expression signature in solid cancers
- A miRNA signature of hypoxia
- MiRNA in pancreatic endocrine and acinar tumors
- The combinational "in cascade" model
- MiRNAs an oncogenes and tumor suppressors (1)
- MiRNAs an oncogenes and tumor suppressors (2)
- MiR15 and miR16 induce apoptosis
- MiR15 and miR16 target multiple genes
- MiR29 family and its role in lung cancer
- MiRNA profiling as diagnostic and prognostic tools
- Unique miRNA signature in CLL progression
- Tcl1 expression regulated by miR-29 and miR-181
- Unique miRNA signature in lung cancer diagnosis
- MiRNA expression in breast cancer
- MiRNA and breast cancer metastases
- MiR21 expression in tumors and chemotherapy
- MiRNA alterations cause cancer predispositions
- Cancer predispositions
- Germline abnormalities in miR15a/16-1 transcript
- Mutation in NZB mice causes the same disease
- Mutations in miRNA primary transcripts
- The "field effect" of miRNA expression
- Chromosomal positions of tumor susceptibility
- Variations in promoters in "modifier" miRNAs
- MiRNAs - the missing link in cancer predisposition
- MicroRNAs as new therapeutic targets and drugs
- Principles of miRNA gene therapy
- MiR15 and miR16 based gene therapy in CLL
- Effects of miR-29s on tumorigenicity of A549 cells
- The genome revolution is not over
- Ultraconserved non-coding genes
- Other ncRNAs could be associated with cancer
- UCG expression profiles classify human cancer
- MiRNA-ncRNA interactions
- Non coding RNAs as oncogenes
- Revisiting the molecular oncology dogma
- Acknowledgment
- Enjoy the ncRNA revolution
Topics Covered
- Central dogma of molecular oncology
- MicroRNA and messenger RNA
- Small RNAs make a big splash
- A model for HE-miRNA mediated control of human haematopoiesis
- Alterations of microRNAs are found in every type of human tumors
- MicroRNAs as oncogenes and tumor suppressors
- miR-15 and miR-16 induce apoptosis by targeting BCL2
- They target multiple apoptosis and cancer related genes
- MicroRNA-29 family
- MiRNA profiling as a new diagnostic and prognostic tool for cancer patients
- A unique miRNA signature is associated with CLL progression
- Cancer predisposition: from epidemiology to genetics
- About humans and mice: same gene, same mutation, same disease
- Mutations in microRNA primary transcripts
- The "field effect" of miRNA expression
- The missing link in cancer predisposition
- MicroRNAs as new therapeutic targets and new drugs
- Principles of miRNA-based gene therapy and in vivo inhibition of miRNA in cancer cells
- Ultraconserved non-coding genes: the new chapter of the textbook
- A never ending revolution: other ncRNAs could be associated with cancer
- UCG expression profiles classify human cancers
- miRNA-ncRNA interactions
- Non-coding RNAs as oncogenes
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Calin, G. (2009, March 30). Genome-wide profiling of microRNAs: from scientist benchside to patient bedside [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 6, 2024, from https://doi.org/10.69645/FYLW4969.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. George Calin has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Genome-wide profiling of microRNAs: from scientist benchside to patient bedside
A selection of talks on Cancer
Hide