Non-alcoholic fatty liver disease (NAFLD): etiology, pathogenesis and current therapeutic approaches

Published on May 30, 2024   22 min

A selection of talks on Clinical Practice

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0:00
I'm Amit Khurana, a Senior Researcher working at the Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, University Hospital Aachen, RWTH University Aachen, located in Aachen, Germany. Today we will learn about the non-alcoholic fatty liver disease, it's etiology, pathology, and current therapeutic approaches.
0:24
The contents of the lecture include the introduction of liver in normal physiological functions, the common metabolic diseases and their rise. Some of the most common metabolic diseases of the liver, non-alcoholic fatty liver disease and its etiology, the pathophysiology of non-alcoholic fatty liver disease, and we will also learn about the current treatment options for non-alcoholic fatty liver disease.
0:52
The liver is an important vital organ. It has remarkable regeneration potential. Some of the most important functions of the liver include the metabolism of major nutrients, maintaining the homeostasis of blood volume, the liver has an active immune system, which prevents a variety of systemic infections. The liver plays an active role in the endocrine control of normal growth. The liver plays an important role in lipid and cholesterol balance. The liver is responsible for the metabolic detoxification of a variety of xenobiotics.
1:30
The role of the liver in metabolism: The liver plays an essential role in the regulation of energy homeostasis and controls important metabolic processes like glycolysis, gluconeogenesis, and fatty acid metabolism. As the liver plays an important role in metabolic processes, unhealthy changes in dietary patterns may lead to the dysfunction of important metabolic processes.
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Non-alcoholic fatty liver disease (NAFLD): etiology, pathogenesis and current therapeutic approaches

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