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Printable Handouts
Navigable Slide Index
- Introduction
- Oral premalignancy: basic concept
- Oral leukoplakia: definition
- Malignant transformation of oral leukoplakia
- Oral leukoplakia development to carcinoma
- Oral leukoplakia follow ups
- Aetiological malignant potential
- Reversible leukoplakia
- Smoking effect on leukoplakia
- Types of oral leukoplakia
- Do reversible lesions become irreversible?
- Leukoplakia lesions and old lichen planus lesions
- Keratosis association with candidal infection
- Leukoplakia lesions after antimycotic treatment
- Leukoplakias and candidal infection
- Yeasts isolated from lesions
- Candida hyphae in sections of oral leukoplakia
- Malignancy relation to candidal infections
- Mycological aetiology of oral mucosal cancer
- HPV as revealed by PAP, ISH, PCR or BLOT
- Clinical malignant potential
- Oral leukoplakia - Malignant transformation
- Leukoplakia clinical examples
- Topographical malignant potential
- Malignant transformation in sublingual keratosis
- Histological malignant potential
- Leukoplakia
- Leukoplakia biopsy
- Treatment of oral premalignant lesions
- Surgical treatment of oral premalignant lesions
- Recurrence and cancer development
- Risk lesions
- Treatment of risk lesions
- Surgical treatment example
- Surgical treatment 5 years follow up
- Surgical treatment premalignant lesion
- Premalignant lesion after antimycotic treatment
- Surgical treatment: skin graft
- Premalignant lesions closure of defects
- Premalignant lesions follow up post-surgery
- Characteristics of lesions and patients
- Clinical type - non homogenous leukoplakia
- Clinical type - homogenous leukoplakia
- Clinical type - Erythroplakia
- Long-term treatment of oral premalignant lesions
- Surgical treatment of premalignant lesions
- Time for cancer to occur
- Risk areas - clinical type
- Non-risk areas - clinical type
- Surgical treated lesions - cancer development
- Non-surgical treated - cancer development
- Logistic regression analysis
- Surgical treatment of premalignant lesions
- Conclusions
- Acknowledgment
Topics Covered
- Malignant transformation of oral leukoplakia
- Oral leukoplakia development to carcinoma
- Oral leukoplakia follow ups
- Aetiological malignant potential
- Types of oral leukoplakia
- Malignancy relation to candidal infections
- Mycological aetiology of oral mucosal cancer
- HPV as revealed by PAP, ISH, PCR or BLOT
- Topographical malignant potential
- Surgical treatment of oral premalignant lesions
- Risk lesions
- Long-term treatment of oral premalignant lesions
- Surgical treatment of premalignant lesions
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Talk Citation
Holmstrup, P. (2017, July 31). White lesions - oral leukoplakia, a premalignant lesion [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 21, 2024, from https://doi.org/10.69645/FQWU1547.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Palle Holmstrup has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
White lesions - oral leukoplakia, a premalignant lesion
Published on July 31, 2017
32 min
Transcript
Please wait while the transcript is being prepared...
0:00
My name is Palle Holmstrup.
I am professor and section head at the School of Dentistry, University of Copenhagen.
And today, we will discuss oral leukoplakia which is a premalignant lesion.
0:17
Oral premalignancy is an important part of dentist activity.
The basic concept of oral premalignancy is to
identify lesions and prevent them from development of cancer.
0:33
The most important and most common premalignant lesion
in the oral cavity is oral leukoplakia.
Oral leukoplakia has been defined in various ways,
usually by the characteristics.
It's defined as a clinical term for a predominantly white lesion of
the oral mucosa that cannot be characterized as any other definable lesion.
It's somehow a strange definition to define
a lesion by the characteristics that it doesn't have,
but several workshops have tried to improve
this definition without any significant result.
So we have to live with this definition of oral leukoplakia.
1:20
The malignant transformation rate of oral leukoplakia has been
reported at annual rates of 2-3%.
And you can ask what is the cause,
and you can also ask whether we can prevent it.
And this will be addressed in the lecture.
1:40
This is an oral leukoplakia.
It is small, red areas which is why it is a non-homogeneous leukoplakia,
demonstrates that it develops a carcinoma after three years of follow-up.