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Hi, my name is Yazan Hassona
and I am from the University of Jordan.
In this seminar,
we will discuss oral ulcers and soreness
due to blood diseases and infections.
It is well known that
a wide range of systemic diseases
may cause oral lesions.
Such lesions might get ulcerated
because of local
oral environmental factors
such as trauma, moisture,
and secondary infection.
The clinical appearance of such lesions,
therefore, may vary
but sometimes resembles aphthous ulcers
and in such cases
they are termed aphthous-like, ulcers.
A useful mnemonic to remember
the main systemic causes
of oral ulcers and soreness is BIGS
where the letter "B" stands for blood
or hematological diseases
such as various anemias
and hematological malignancies.
"I" stands for infective causes,
which are mainly viral infections
but also bacterial, fungal,
and protozoal infections
may cause oral ulcers.
"G" for gastrointestinal
such as Crohn's and celiac disease,
"S" for skin or mucocutaneous diseases
that include particularly lichen planus
and occasionally other skin diseases,
such as pemphigoid, pemphigus,
and erythema multiforme.
There are also other systemic causes
of oral ulcers and soreness
such as traumatic diseases
and some endocrine disturbances.
we'll discuss only hematological
and infective causes of oral ulcers
Other causes are discussed
in other seminars of this series.