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0:00
My name is Nicholas Kalavrezos,
and I'm a Consultant in
Head & Neck/Reconstructive Surgery
at University College London Hospital.
The topic of my presentation today
is "Lumps and Bumps
in the Mouth and Lips".
0:17
Lumps and bumps of the mouth
and the lips, broadly speaking,
belong in
four different categories:
malformations,
namely congenital lesions,
traumatic, infections of
inflammatory origin. And of course,
last but not least,
neoplasias.
0:38
A typical appearance of a lesion
from the first category,
from the malformations,
are the low flow malformations
which are manifested
as bluish branchial
compression lesions.
0:54
Capillary haemangiomas, indeed,
belong also
in the malformation category.
And have usually
a more subtle appearance
of a bluish manifestation.
1:05
I will skip the rather typical
traumatic lesions.
And also at this point,
the infections,
and inflammatory manifestations.
And I will concentrate,
in the next few slides,
in the most important pathology
that may be manifested
as a swelling of the mouth or
of the lip.
Indeed,
these are the oral malignant
and pre-malignant conditions.
1:29
At this point, I will emphasize
some of the facts
related to the most important
underlying pathology
of the mouth and lips swelling,
namely the potential
presence of cancer.
The most common fact
and the most known fact about
oral cancer
can be summarized as, oral cancer
is the eighth most common
solid tumor worldwide.
It represents 4%
of all malignancies.
There are 42,000 new cases
in Europe annually,
32,000 new cases
in the US annually.
And indeed,
more than 5,000 new patients
in the UK every year.
And despite the advances
in surgery and radiotherapy,
the mortality rate has essentially
remained unchanged for decades
with a 5-year survival rate of 50%.
Broadly speaking,
this is indeed correct.
I will make a small addition to say
that the advances
in reconstructive surgery,
over the last 10-20 years,
do seem to start having an impact
on the overall survival rate.
And therefore, I would possibly
be able to revise this slide
or the survival rate on this slide,
still on anecdotal basis,
from 50% rather to 55% to 60%.
Regardless of this fact, though,
we have to know that oral cancer
remains a major killer
with a rather still dim
overall survival rate.
