Homeotic genes in Drosophila's bithorax complex - The legacy of Ed Lewis

Published on September 29, 2008 Updated on July 31, 2018   28 min

Other Talks in the Category: Genetics & Epigenetics

0:00
Hi, my name is François Karch. I'm a faculty member at the University of Geneva in Switzerland. In this presentation, I will introduce you to the world of Homeotic genes also known as Hox gene. I will focus on the Homeotic gene of the Bithorax complex in Drosophila. Hox genes play a fundamental role in the body axis of all living animals. They specify the structures that form along the anterior posterior axis. Hox gene has been conserved through evolution from Drosophila where they had been discovered to humans.
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Homeotic gene has been discovered in Drosophila thanks to the amenability of this organism for genetic studies. This slide shows you a wild-type female. We observe easily the segment that forms the body of the fly. There is the head and the thorax. The thorax is formed of three thoracic segments, T1, T2, and T3. From these three segments develop three pair of legs, which are the characteristics of all insects. There is then the abdomen, which is composed of eight abdominal segments that are not all visible in the adult fly. Will mention also here, the pair of wings which developed from the second thoracic segment T2 and a pair of haltere , that developed from the third thoracic segment T3. On the left is again our wild-type fly,
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Homeotic genes in Drosophila's bithorax complex - The legacy of Ed Lewis

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