• Statistical Genetics of Complex Diseases
• 38 min
  1. Population genetics considerations

  • Prof. Nan Laird
• 39 min
  2. Gene-by-environment interaction: study designs and analytical methods

  • Prof. L. Adrienne Cupples
• 59 min
  3. Analysis of SNP haplotypes

  • Prof. Lyle Palmer
• 36 min
  4. Statistical issues in epidemiological studies of gene-environment interaction

  • Dr. Peter Kraft
  • Prof. Donna Spiegelman
• Molecular Epidemiology of Pulmonary Diseases
• 57 min
  5. Molecular epidemiology of lung cancer

  • Prof. David Christiani
• 34 min
  6. Ethical issues in molecular epidemiology and studies of gene-environment interactions

  • Dr. Richard Sharp
• Autoimmune Diffuse Connective Tissue Diseases
• 29 min
  7. Environmental scleroderma: the evidence for putative triggers

  • Prof. Maureen Mayes
• Drug-Induced Disease
• 35 min
  8. Drug-induced lupus

  • Prof. Evelyn Hess
• Archived Lectures *These may not cover the latest advances in the field
• 41 min
  9. Biomarkers of exposure

  • Prof. Thomas Smith
• 43 min
  10. GIS and spatial statistics

  • Prof. Louise Ryan
• 47 min
  11. Gene-by-environment interactions in COPD

  • Prof. Edwin Silverman
• 40 min
  12. Occupational and environmental influences on the development and course of lupus

  • Dr. Glinda Cooper
• 54 min
  13. Genetic susceptibility in granulomatous disorders: chronic beryllium disease and sarcoidosis

  • Prof. Lee Newman
• 29 min
  14. Indians, twins and scleroderma: genetic and genomic studies

  • Prof. Frank Arnett
• 27 min
  15. Gene by environment interaction in asthma

  • Prof. Scott Weiss
• 42 min
  16. Molecular epidemiology of lung cancer

  • Prof. David Christiani
• 18 min
  17. Racial and ethnic variation in systemic lupus erythematosus and systemic sclerosis (scleroderma)

  • Dr. Patricia Fraser
• 47 min
  18. Infectious environmental factors and systemic lupus erythematosus

  • Prof. Judith James

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. University hospital
3. Potential immunologic agents
4. Drugs implicated with autoimmune syndromes
5. Lab features with drug related Lupus
6. Minocycline Lupus syndrome
7. Chlorpromazine induces apoptosis
8. Drug Lupus with sulphasalazine
9. Statin drugs
10. Disorders associated with antiphospholipid Ab.
11. Biologics with Lupus profiles
12. Patients on entanercept
13. I.V. anti TNF alpha with low dose MTX
14. Autoantibody testing
15. Anti-nuclear/anti-smooth-muscle antibodies
16. Drug/toxin eosinophilic myositis
17. Drugs associated with vasculitis
18. Examples of ethnopharmacology
19. N-acetyltransferase (NAT2)
20. Acetylator effects on metabolic fate of drugs
21. Thoughts about "drug toxicity" phenotypes
22. Fate of environmental factors
23. Proposed guidelines for EARDs
24. Stage 1,2 and 3
25. Refining the proposed guidelines for EARDs

Topics Covered

• The occurrence of drug and environment-related lupus and lupus-like syndromes
• The medications that have been reported in association with autoimmune symptoms and syndromes
• The major associations and cause(s) of these commonly noted clinical syndromes

Links

Series:

• Gene-Environment Interactions

Categories:

• Genetics & Epigenetics
• Pharmaceutical Sciences

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Evelyn Hess has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.