Clinical importance of pharmacogenetic polymorphisms affecting drug metabolism

Published on October 1, 2007 Updated on July 31, 2016   39 min

Other Talks in the Series: Drug Metabolizing Enzymes

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My name is Julia Stingl. Former name was Kirchheiner. I am a Professor of Clinical Pharmacology at the University Bonn. And I will talk about clinical importance of pharmacogenetic polymorphisms affecting drug metabolism.
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Part 2, Internal Medicine.
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We have now more than 30 years of pharmacogenetic research. But still we may ask ourselves, do we really use it? Where is the translation into the clinics? And these are the questions that are most urgent. What is the patient's benefit? And how could we increase drug safety with the use of pharmacogenetics? Or has our drug therapy been improved by genetic diagnostics? So to come closer to an answer of these questions, I would like to talk about pharmacogenetics in internal medicine and, first, give you a short introduction to the pharmacogenetics variants impacting drug therapy in internal medicine.
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Clinical importance of pharmacogenetic polymorphisms affecting drug metabolism

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