Arylamine N-acetyltransferases 1

Published on October 1, 2007 Updated on July 28, 2016   31 min

Other Talks in the Series: Drug Metabolizing Enzymes

Arylamine N-acetyltransferases, I'm Edith Sim. I'm going to be talking about a family of drug metabolizing enzymes. And I have been working on this family of enzymes for more than 20 years. And this represents an update on what was presented previously in a former version of a Henry Stewart talk.
As a code, slides with an "S" in the upper left hand corner contain advanced supplementary information in addition to the core material which is presented throughout the talk. Arylamine N-acetyltransferases
are cytosolic enzymes which are commonly called phase II drug metabolizing enzymes. They're around 30-34 kDa in size, and are widespread amongst eukaryotes and prokaryotes. They were first recognized for their role in the N-acetylation of hydrazines and arylamines.