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- 2023
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1. Planning and response to COVID-19: lessons from China and South-East Asia
- Prof. Annelies Wilder-Smith
- 2022
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2. The emergence of the SARS-CoV-2 Omicron variant
- Prof. Emma Thomson
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3. How is Omicron different?
- Prof. Emma Thomson
- 2021
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5. Potential of ‘long-COVID’ in triggering chronic co-pathologies
- Dr. İmdat Eroğlu
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6. SARS-CoV-2 monoclonal antibody testing in vivo
- Prof. Michael Diamond
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7. mRNA COVID-19 vaccine efficacy in recovered vs COVID-naive individuals
- Prof. E. John Wherry
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8. SARS-CoV-2 variants: implications for immunity and vaccine development
- Prof. Danny Altmann
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10. SARS-COV-2 human monoclonal antibody therapy update
- Prof. James Crowe
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11. Emergence of blood clotting disorders resulting from COVID vaccines inoculations
- Prof. Dr. Sabine Eichinger
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12. SARS-CoV-2 evolution within and between individuals
- Prof. Katia Koelle
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13. Identifying SARS-CoV-2 proteases
- Prof. Dr. Christa E. Müller
- Prof. Dr. Michael Gütschow
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14. Genetic surveillance and the emergence of SARS-CoV-2 variants
- Prof. Emma Thomson
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15. The COVID-19 outbreak: April 2021 update
- Prof. Jonathan Temte
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16. ABO blood groups and SARS-CoV-2 susceptibility
- Dr. Sean Stowell
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17. Impact of COVID-19 on neuropsychiatric disorders and mental health
- Prof. Anthony David
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18. The immune system response to the SARS-CoV-2 virus: March 2021 update
- Prof. Paul Klenerman
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23. SARS-CoV-2 vaccine rollout campaigns
- Prof. Luis Graca
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25. Interspecies transmission of SARS-CoV-2
- Dr. Dalan Bailey
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26. Complement activation in COVID-19
- Prof. Jeffrey Laurence
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27. Human movement patterns and local spread of COVID-19
- Prof. Ben Cowling
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28. SARS-CoV-2 mutations: phenotypes and implications for vaccine development
- Prof. David Montefiori
- 2020
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29. The immune system response to the SARS-CoV-2 virus: December 2020 update
- Prof. Paul Klenerman
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30. Triage and end of life care planning in COVID-19
- Prof. Robin Taylor
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31. Natural killer cells as COVID-19 therapy
- Dr. Philippa Kennedy
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32. Update on the SNG001 drug, an INFβ therapy for COVID-19
- Prof. Stephen Holgate
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34. Identification of a new coronavirus-specific RNA export protein complex
- Dr. Montse Bárcena-Martin
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35. The neurological symptoms of COVID-19
- Dr. Michael Zandi
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36. Imperial College London’s saRNA Vaccine - COVAC1
- Dr. Katrina Pollock
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37. Interferon-α2b as a therapy for COVID-19
- Prof. Eleanor N. Fish
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38. Potential long-term health effects of a SARS-CoV-2 infection
- Prof. Danny Altmann
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39. The COVID-19 coronavirus outbreak: October 2020 update
- Prof. Jonathan Temte
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41. Rheumatic diseases and COVID-19
- Dr. Zachary Wallace
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42. The cardiovascular complications of SARS-CoV-2 infection
- Prof. Srihari Naidu
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43. Medical wearable devices for tracking symptoms of COVID-19
- Prof. John Rogers
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44. Risk of re-emergence of COVID-19 after exit from lockdown
- Dr. Leonardo Lopez
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45. The evolutionary origin of SARS-CoV-2
- Dr. Feng Gao
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46. Predicting COVID-19 outbreaks by measuring SARS-CoV-2 RNA in sewage sludge
- Prof. Jordan Peccia
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47. Approaches for elucidating genetic susceptibility to SARS-CoV-2
- Dr. Kenneth Baillie
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48. The immune system response to the SARS-CoV-2 virus: July 2020 update
- Prof. Paul Klenerman
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49. The impact of COVID-19 in the elderly and in care homes
- Dr. David Strain
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50. Human challenge trials for vaccines against COVID-19
- Prof. Peter Smith
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51. The development of SARS-CoV-2 vaccines
- Prof. Peter Hotez
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52. Convalescent plasma therapy as a treatment for COVID-19
- Dr. Manu Shankar-Hari
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53. Remdesivir COVID-19 clinical trial
- Prof. Mahesh Parmar
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54. Nanotechnologies in the fight against coronaviruses
- Prof. Sabine Szunerits
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55. The COVID-19 coronavirus outbreak: May 2020 update
- Prof. Jonathan Temte
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56. INFβ therapy for COVID-19: the new SNG001 drug
- Prof. Stephen Holgate
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57. Strategies for exiting the lockdown
- Prof. David McCoy
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58. SARS-CoV-2 human monoclonal antibody therapy
- Prof. James Crowe
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59. An FDA approved salivary test for SARS-CoV-2 infection
- Prof. Andrew Brooks
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60. Development of an intranasal vaccine for SARS-CoV-2
- Dr. Scot Roberts
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61. The immune system response to the SARS-CoV-2 virus: an update
- Prof. Paul Klenerman
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62. A novel AIOD-CRISPR system for diagnosis of SARS-CoV-2
- Prof. Changchun Liu
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63. Development of PRO-140 (Leronlimab) as a treatment for COVID-19
- Dr. Jacob Lalezari
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64. COVID-19 epidemiology and potential treatments: follow up interview
- Prof. Ralph Baric
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65. SARS-CoV-2 vaccine development: where are we now?
- Prof. Gary Kobinger
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66. SARS-CoV-2: What we need to know and possible future therapies
- Prof. Stanley Perlman
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67. SARS-CoV-2 vaccine: current biological targets and considerations
- Dr. Adolfo Garcia-Sastre
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68. The current understanding of the biology of the SARS-CoV-2 virus
- Prof. Peter Palese
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70. The immune system response to the SARS-CoV-2 virus
- Prof. Paul Klenerman
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71. SARS-CoV-2 vaccine development
- Prof. Stanley Plotkin
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72. The COVID-19 outbreak: an update on the SARS-CoV-2 virus
- Prof. Ralph Baric
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73. The COVID-19 coronavirus outbreak: a current view
- Prof. Jonathan Temte
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74. The COVID-19 coronavirus outbreak: March 2020 update
- Prof. Jonathan Temte
Topics Covered
- Type of modelling and initial research rationale
- Reliability of modelling results
- Caution to be applied when analysing and interpreting results of models
- Measures to avoid second wave of infection
- Conditions that could lead to a second wave
- Role of acquired immunity in the dynamics of a second wave
Biography
Dr Leonardo Lopez obtained his PhD from the Research Institute for Signals, Systems and Computational Intelligence in Buenos Aires, focusing on socio-environmental elements as modulators of the main variables that define epidemiological dynamics. Currently, he is a postdoctoral researcher at the Climate and Health research group at the Barcelona Institute for Global Health, where he is focusing on epidemiological modelling using multi-agent and individual-based theory models.
Links
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Talk Citation
Lopez, L. (2020, August 26). Risk of re-emergence of COVID-19 after exit from lockdown [Audio file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 27, 2024, from https://hstalks.com/bs/4396/.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Leonardo Lopez has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A selection of talks on Clinical Practice
Transcript
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0:00
Interviewer: Dr. Leonardo Lopez, thank you very much for
taking the time to do this interview with us today to discuss
your recently published research in Nature regarding
the modeling of the current COVID-19 pandemic progression in Europe,
and the prediction of second waves of infections
which you have projected could easily take place,
which as it turns out,
is starting to take place at the moment across Europe.
Let me jump right in and first of all,
ask you about the type of modeling you did
and the questions you were initially trying to address with this research.
Prof. Lopez: Yes. The kind of model we carry out is what
in bibliography is normally known as compartmental or population-based model.
In this kind of model, the population under study,
this is like a country or an autonomous region,
a county, et cetera,
is divided into different compartments
that represent different epidemiological characteristics.
The best model that normally is used
the SEIR model where basically the population is divided in four categories.
On one hand, you have the susceptible population to the disease,
and this is the population that can be infected.
Then you have the exposed population to the pathogen,
that is the population that is exposed to the pathogen
and then enters to the incubation process.
The infectious population or infected,
this is the population that has the capacity of infecting others in the population.