Adaptive clinical trials: conclusion and future directions

Published on August 31, 2017   43 min

Other Talks in the Series: Adaptive Clinical Trial Design

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Welcome to the last lecture of the "Adaptive Clinical Trials" course. In this last lecture, we will talk about the conclusion and the future directions of the adaptive clinical trials. My name is Yu Shyr, I'm the director of the Vanderbilt Center for Quantitative Sciences.
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In today's lecture, we will discuss several topics. Again, I will start to review the definition of adaptive clinical trial. You have been in this course for a while, to the several different lectures. I hope you enjoyed that. And in the last lecture review, what is the definition of an adaptive clinical trial. Then we will talk about the type of adaptive trials, then we will talk about biomarker-adaptive clinical trials design. If you took my first lecture which is overview, if you still remember what I said, I said we will come back, in the very last lecture, to talk more about biomarker adaptive clinical trial design because we are going to see more and more talkative therapy using biomarker-based to study. So today, in this very last lecture, before I finish all this entire course series, I would like to give you some idea about the in-depth discussion about biomarker-adaptive clinical trial design. Then I will give you several examples of phase I, II and III adaptive trial design. That's kind of the end of this entire course series and I would end with the last slide; talk about what I feel, what I think about the future direction of the adaptive clinical trials design. So this is the highlight of your last lecture.

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Adaptive clinical trials: conclusion and future directions

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