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- Human Population Genetics: An Overview
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1. Modern human origins
- Prof. Richard Klein
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2. History and geography of human genetic diversity I
- Prof. Luigi Luca Cavalli-Sforza
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3. History and geography of human genetic diversity II
- Prof. Luigi Luca Cavalli-Sforza
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4. Cultural evolution
- Prof. Marcus Feldman
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5. The human genomes
- Prof. Gil McVean
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6. Human population structure
- Prof. Noah Rosenberg
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7. The signature of local adaptations in human polymorphism data
- Dr. Anna Di Rienzo
- The Human Genome Project
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8. The HapMap project
- Prof. Andrew Clark
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9. Major gene families in humans and their evolutionary history
- Prof. Yoshihito Niimura
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10. Evolution of human mitochondrial DNA variations
- Prof. Toomas Kivisild
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11. Ethical issues in human population genetics
- Prof. Henry Greely
- Important Phenotypic Phenomena
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12. Evolution: how genes and their variation got here
- Prof. Kenneth Weiss
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13. The genetic component to diabetes
- Dr. Nancy Cox
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14. Genetics of breast and ovarian cancer
- Prof. Jeffrey Weitzel
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15. Colorectal cancer and the rare variant hypothesis
- Prof. Sir Walter Bodmer
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16. Genetic diseases in the Jewish population
- Prof. Neil Risch
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17. The genetics of French Canadians
- Dr. Bernard Brais
- Dr. Bertrand Desjardins
- Prof. Damian Labuda
- Dr. Marc St-Hilaire
- Prof. Marc Tremblay
- Prof. Helene Vezina
- Historical and Geographical Genetic Variation
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18. Human genetic variation of Africa
- Prof. Joanna Mountain
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19. Genetics of Pakistani populations in an Asian and global context
- Prof. S. Qasim Mehdi
- Archived Lectures *These may not cover the latest advances in the field
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20. The genetics of breast and ovarian cancer
- Dr. Piri Welcsh
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21. Historical and geographical genetic variation: Europe
- Prof. Antonio Torroni
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22. Linguistic evolution
- Dr. Merritt Ruhlen
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23. Human microsatellite and minisatellite DNA polymorphisms
- Dr. James Weber
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24. Human population genetics: lifespan
- Prof. Kaare Christensen
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25. History and geography of human genetic diversity III
- Prof. Luigi Luca Cavalli-Sforza
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26. Major gene families in humans and their evolutionary history
- Prof. Yoshihito Niimura
- Prof. Masatoshi Nei
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27. Natural selection and sequence polymorphism
- Prof. Austin Hughes
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28. Human Y chromosome phylogenetics and phylogeography
- Prof. Peter Underhill
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29. The peopling of the Americas: new insights from genetic studies
- Dr. Theodore Schurr
Printable Handouts
Navigable Slide Index
- Introduction
- Contents
- Multigene family (1)
- Multigene family (2)
- Color vision genes
- Red/ green-pigment gene duplication
- Color vision genes in New World Monkeys
- Full trichromatic vision in primates
- Evolutionary models for multigene families
- Olfactory receptors (1)
- Olfactory receptors (2)
- OR gene expression
- Features of ORs
- The olfactory system uses combinatorial coding
- OR genes in humans
- OR genes in the human genome
- Distribution of OR genes in human chromosomes
- Evolutionarily closely related genes
- Organization of OR genomic clusters
- Summary of the observations
- Comparison of OR genes: humans vs. mice (1)
- Comparison of OR genes: humans vs. mice (2)
- Comparison of OR genomic clusters
- Chromosomes translocation occurred in mouse
- The mouse cluster is usually larger
- Less functional OR human genes (1)
- Less functional OR human genes (2)
- Gene duplications after human-mouse divergence
- Phylogenetic tree of the entire set of OR genes
- No. of inactivated functional genes in the MRCA
- Estimated number of functional genes
- Evolution of OR genes in vertebrates (1)
- Evolution of OR genes in vertebrates (2)
- Number of OR genes in six species
- Phylogenetic tree from 5 species
- Condensed tree (70% level) for 310 OR genes
- Number of functional OR genes in different groups
- Evolutionary dynamics of vertebrate OR genes
- Summary
- Other chemosensory receptor genes
- Receptors for chemosensation
- Vomeronasal receptors
- Taste receptors
- No. of chemosensory receptor genes in vertebrates
- Conclusions
- Thank you
Topics Covered
- Multigene family
- Olfactory Receptors (ORs)
- OR genes in humans
- Comparison of OR genes between humans and mice
- Evolution of OR genes in vertebrates
- Other chemosensory receptor genes
Talk Citation
Niimura, Y. and Nei, M. (2007, October 1). Major gene families in humans and their evolutionary history [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 26, 2024, from https://hstalks.com/bs/311/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Yoshihito Niimura has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
- Prof. Masatoshi Nei has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.